Combining Desferriferrioxamine B and 1-Hydroxy-2-Piperidone ((PIPO)H) to Chelate Zirconium. Solution Structure of a Model Complex of the 89ZrZr-DFOcyclo-mAb Radioimmunoconjugate

89Zr-immunoPET is a hot topic as 89Zr cumulates the advantages of 64Cu and 124I without their drawbacks. We report the synthesis of a model ligand of a chiral bioconjugable tetrahydroxamic chelator combining the desferriferrioxamine B siderophore and 1-hydroxy-2-piperidone ((PIPO)H), a chiral cyclic...

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Veröffentlicht in:ChemPlusChem (Weinheim, Germany) Germany), 2024-07, Vol.89 (7), p.e202400062
Hauptverfasser: Mangin, Floriane, Fonquernie, Osian, Jewula, Pawel, Brandès, Stéphane, Penouilh, Marie-José, Bonnin, Quentin, Vincent, Bruno, Espinosa, Enrique, Aubert, Emmanuel, Meyer, Michel, Chambron, Jean-Claude
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Sprache:eng
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