Defect Induced Structural Transition and Lipase Immobilization in Mesoporous Aluminum Metal‐Organic Frameworks

The transition from disorder to order and structural transformation are distinctive metal‐organic framework (MOF) features. How to adapt or control both behaviors in MOF has rarely been studied. In this case, we demonstrate that our successful synthesis of [Al(OH)(PDA)]n (AlPDA‐53‐DEF, AlPDA‐53‐H, and AlPDA‐68) with H2PDA=4,4′‐[1,4‐phenylenebis(ethyne‐2,1‐diyl)]‐di benzoic acid has shown the intricate world of Aluminum Metal‐Organic Frameworks (Al‐MOFs). It offers profound insights into defect structures to order and transformations. AlPDA‐53‐DEF, in particular, revealed a fascinating interplay of various pore sizes within both micro and mesoporous regions, unveiling a unique lattice rearrangement phenomenon upon solvent desorption. Defects and disorders emerged as crucial impacts of transforming AlPDA‐53‐DEF, with its initially imperfect crystallinity, into the highly crystalline, hierarchically porous AlPDA‐53‐H. The synthesis of AlPDA‐53‐DEF, AlPDA‐53‐H, and AlPDA‐68 with insights into Aluminum Metal‐Organic Frameworks (Al‐MOFs), their defect structures, lattice rearrangement, and the role of defects and disorders in the transformation from AlPDA‐53‐DEF to AlPDA‐53‐H.