Ancestral aneuploidy and stable chromosomal duplication resulting in differential genome structure and gene expression control in trypanosomatid parasites

Aneuploidy is widely observed in both unicellular and multicellular eukaryotes, usually associated with adaptation to stress conditions. Chromosomal duplication stability is a tradeoff between the fitness cost of having unbalanced gene copies and the potential fitness gained from increased dosage of...

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Veröffentlicht in:	Genome research 2024-04, Vol.34 (3), p.441
Hauptverfasser:	Reis-Cunha, João L, Pimenta-Carvalho, Samuel A, Almeida, Laila V, Coqueiro-Dos-Santos, Anderson, Marques, Catarina A, Black, Jennifer A, Damasceno, Jeziel, McCulloch, Richard, Bartholomeu, Daniella C, Jeffares, Daniel C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Chromosome Duplication Chromosomes Evolution, Molecular Gene expression Gene Expression Regulation Genome, Protozoan Parasites Phylogeny Post-transcription Reproductive fitness Supernumerary Trypanosomatina - genetics
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