EGFR/CEP7 high polysomy is separate and distinct from EGFR amplification in glioblastoma as determined by fluorescence in situ hybridization

EGFR amplification in gliomas is commonly defined by an EGFR/CEP7 ratio of ≥2. In testing performed at a major reference laboratory, a small subset of patients had ≥5 copies of both EGFR and CEP7 yet were not amplified by the EGFR/CEP7 ratio and were designated high polysomy cases. To determine whet...

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Veröffentlicht in:	Journal of neuropathology and experimental neurology 2024-04, Vol.83 (5), p.338-344
Hauptverfasser:	Wilcock, Diane M, Goold, Eric, Zuromski, Lauren M, Davidson, Christian, Mao, Qinwen, Sirohi, Deepika
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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