Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser—A prospective, controlled study

Background Pulsed‐dye lasers (PDL) are one of the standard therapies for rosacea, but alternatives are needed. Aims To compare the efficacy and safety of the variable‐sequenced, large‐spot 532 nm KTP laser to the 595 nm PDL in treating rosacea. Materials and Methods A prospective, controlled, evalua...

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Veröffentlicht in:Journal of cosmetic dermatology 2024-07, Vol.23 (7), p.2443-2449
Hauptverfasser: Nguyen, Lynhda, Dierckxsens, Cathy, Kerscher, Martina, Hartjen, Anna, Schneider, Stefan W., Herberger, Katharina
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container_end_page 2449
container_issue 7
container_start_page 2443
container_title Journal of cosmetic dermatology
container_volume 23
creator Nguyen, Lynhda
Dierckxsens, Cathy
Kerscher, Martina
Hartjen, Anna
Schneider, Stefan W.
Herberger, Katharina
description Background Pulsed‐dye lasers (PDL) are one of the standard therapies for rosacea, but alternatives are needed. Aims To compare the efficacy and safety of the variable‐sequenced, large‐spot 532 nm KTP laser to the 595 nm PDL in treating rosacea. Materials and Methods A prospective, controlled, evaluator‐blinded study. Patients were treated with either a KTP or PDL with 1–3 sessions at intervals of 6–8 weeks. A follow‐up visit was scheduled on Week 6 post‐treatment. Clinical outcome was assessed by computer‐assisted analysis and by patients and two blinded dermatologists. Pain intensity during treatment and adverse events were documented. Results Forty‐five patients (mean age 51 years) were allocated in a 2:1 ratio to either the KTP or PDL. Erythema in both treatment arms decreased significantly (p 
doi_str_mv 10.1111/jocd.16300
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Aims To compare the efficacy and safety of the variable‐sequenced, large‐spot 532 nm KTP laser to the 595 nm PDL in treating rosacea. Materials and Methods A prospective, controlled, evaluator‐blinded study. Patients were treated with either a KTP or PDL with 1–3 sessions at intervals of 6–8 weeks. A follow‐up visit was scheduled on Week 6 post‐treatment. Clinical outcome was assessed by computer‐assisted analysis and by patients and two blinded dermatologists. Pain intensity during treatment and adverse events were documented. Results Forty‐five patients (mean age 51 years) were allocated in a 2:1 ratio to either the KTP or PDL. Erythema in both treatment arms decreased significantly (p &lt; 0.01). Clinical evaluation revealed high improvement. Mean pain intensity was significantly lower with the KTP (2.5/10) than with the PDL (4.1/10). Both lasers showed a good safety profile. Relevant purpura was only seen in the PDL group. Conclusions Both the variable‐sequenced, large‐spot KTP and the PDL demonstrated comparable efficacy in treatment of rosacea. Regarding safety, the KTP exhibited fewer post‐treatment reactions. The KTP might serve as a potential alternative to PDL in the treatment of rosacea.</description><identifier>ISSN: 1473-2130</identifier><identifier>ISSN: 1473-2165</identifier><identifier>EISSN: 1473-2165</identifier><identifier>DOI: 10.1111/jocd.16300</identifier><identifier>PMID: 38600654</identifier><language>eng</language><publisher>England</publisher><subject>erythema ; KTP ; pulsed dye laser ; rosacea ; telangiectasia</subject><ispartof>Journal of cosmetic dermatology, 2024-07, Vol.23 (7), p.2443-2449</ispartof><rights>2024 The Authors. published by Wiley Periodicals LLC.</rights><rights>2024 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3240-b32c937c790bbb9b17fed14e44e86e7bccbd7037038f231f6924928f9964456f3</cites><orcidid>0000-0002-1258-6390</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjocd.16300$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjocd.16300$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,1417,11562,27924,27925,45574,45575,46052,46476</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38600654$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nguyen, Lynhda</creatorcontrib><creatorcontrib>Dierckxsens, Cathy</creatorcontrib><creatorcontrib>Kerscher, Martina</creatorcontrib><creatorcontrib>Hartjen, Anna</creatorcontrib><creatorcontrib>Schneider, Stefan W.</creatorcontrib><creatorcontrib>Herberger, Katharina</creatorcontrib><title>Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser—A prospective, controlled study</title><title>Journal of cosmetic dermatology</title><addtitle>J Cosmet Dermatol</addtitle><description>Background Pulsed‐dye lasers (PDL) are one of the standard therapies for rosacea, but alternatives are needed. Aims To compare the efficacy and safety of the variable‐sequenced, large‐spot 532 nm KTP laser to the 595 nm PDL in treating rosacea. Materials and Methods A prospective, controlled, evaluator‐blinded study. Patients were treated with either a KTP or PDL with 1–3 sessions at intervals of 6–8 weeks. A follow‐up visit was scheduled on Week 6 post‐treatment. Clinical outcome was assessed by computer‐assisted analysis and by patients and two blinded dermatologists. Pain intensity during treatment and adverse events were documented. Results Forty‐five patients (mean age 51 years) were allocated in a 2:1 ratio to either the KTP or PDL. Erythema in both treatment arms decreased significantly (p &lt; 0.01). Clinical evaluation revealed high improvement. Mean pain intensity was significantly lower with the KTP (2.5/10) than with the PDL (4.1/10). Both lasers showed a good safety profile. Relevant purpura was only seen in the PDL group. Conclusions Both the variable‐sequenced, large‐spot KTP and the PDL demonstrated comparable efficacy in treatment of rosacea. Regarding safety, the KTP exhibited fewer post‐treatment reactions. 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Aims To compare the efficacy and safety of the variable‐sequenced, large‐spot 532 nm KTP laser to the 595 nm PDL in treating rosacea. Materials and Methods A prospective, controlled, evaluator‐blinded study. Patients were treated with either a KTP or PDL with 1–3 sessions at intervals of 6–8 weeks. A follow‐up visit was scheduled on Week 6 post‐treatment. Clinical outcome was assessed by computer‐assisted analysis and by patients and two blinded dermatologists. Pain intensity during treatment and adverse events were documented. Results Forty‐five patients (mean age 51 years) were allocated in a 2:1 ratio to either the KTP or PDL. Erythema in both treatment arms decreased significantly (p &lt; 0.01). Clinical evaluation revealed high improvement. Mean pain intensity was significantly lower with the KTP (2.5/10) than with the PDL (4.1/10). Both lasers showed a good safety profile. Relevant purpura was only seen in the PDL group. Conclusions Both the variable‐sequenced, large‐spot KTP and the PDL demonstrated comparable efficacy in treatment of rosacea. Regarding safety, the KTP exhibited fewer post‐treatment reactions. The KTP might serve as a potential alternative to PDL in the treatment of rosacea.</abstract><cop>England</cop><pmid>38600654</pmid><doi>10.1111/jocd.16300</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-1258-6390</orcidid><oa>free_for_read</oa></addata></record>
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subjects erythema
KTP
pulsed dye laser
rosacea
telangiectasia
title Rosacea treatment with 532 nm KTP versus 595 nm pulsed dye laser—A prospective, controlled study
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