A case series of post-infectious chikungunya myeloradiculoneuropathy

Chikungunya fever is an arboviral illness caused by chikungunya virus (CHIKV) and transmitted by the bite of Aedes aegypti and Aedes albopictus. It is an RNA virus belonging to the genus Alphavirus and family Togaviridae. We present a case series of three patients with chikungunya illness developing...

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Veröffentlicht in:Journal of the neurological sciences 2024-04, Vol.459, p.122955-122955, Article 122955
Hauptverfasser: Selvam, Suresh, Youron, Padma, Singh, Harpreet, Shree, Ritu, Suri, Vikas, Goyal, Manoj, Modi, Manish, Bhalla, Ashish
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container_title Journal of the neurological sciences
container_volume 459
creator Selvam, Suresh
Youron, Padma
Singh, Harpreet
Shree, Ritu
Suri, Vikas
Goyal, Manoj
Modi, Manish
Bhalla, Ashish
description Chikungunya fever is an arboviral illness caused by chikungunya virus (CHIKV) and transmitted by the bite of Aedes aegypti and Aedes albopictus. It is an RNA virus belonging to the genus Alphavirus and family Togaviridae. We present a case series of three patients with chikungunya illness developing para/post-infectious myeloradiculoneuropathy.These patients developed neurological symptoms in the form of bilateral lower limb weakness with sensory and bowel involvement after the recovery from the initial acute episode of chikungunya fever. Clinical examination findings suggested myeloradiculoneuropathy with normal Magnetic Resonance Imaging of the Spine, with the nerve conduction study showing sensorimotor axonal polyneuropathy. All the patients were treated with 1 g of methylprednisolone once a day for five days, and case 2 was given intravenous immunoglobulin also. In the follow-up, cases 1 and 2 showed complete recovery without recurrence, and case 3 did not show improvement at one month.
doi_str_mv 10.1016/j.jns.2024.122955
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subjects Aedes
Animals
Chikungunya fever
Chikungunya Fever - complications
Chikungunya Fever - diagnostic imaging
Chikungunya Fever - drug therapy
Chikungunya virus - genetics
EMG (electromyography)
Humans
Insect Vectors
IVIG (intravenous immunoglobulins)
Myeloradiculopathy
NCS (nerve conduction study)
title A case series of post-infectious chikungunya myeloradiculoneuropathy
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