Engineering of the Long-Main-Chain Monomer-Incorporating Polyhydroxyalkanoate Synthase PhaCAR for the Biosynthesis of Poly(R)-3-hydroxybutyrate-co-6-hydroxyhexanoate

Polyhydroxyalkanoate (PHA) synthases (PhaCs) are useful and versatile tools for the production of aliphatic polyesters. Here, the chimeric PHA synthase PhaCAR was engineered to increase its capacity to incorporate unusual 6-hydroxyhexanoate (6HHx) units. Mutations at positions 149 and 314 in PhaCAR...

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Veröffentlicht in:	Biomacromolecules 2024-05, Vol.25 (5), p.2973
Hauptverfasser:	Hozumi, Yuka, Hachisuka, Shin-Ichi, Tomita, Hiroya, Kikukawa, Hiroshi, Matsumoto, Ken'ichiro
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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