Mdivi-1: Effective but complex mitochondrial fission inhibitor

Mdivi-1, Mitochondrial DIVIsion inhibitor 1, has been widely employed in research under the assumption that it exclusively influences mitochondrial fusion, but effects other than mitochondrial dynamics have been underinvestigated. This paper provides transcriptome and DNA methylome-wide analysis for...

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Veröffentlicht in:	Biochemical and biophysical research communications 2024-05, Vol.710, p.149886, Article 149886
Hauptverfasser:	Ahn, Seor I, Choi, Sung Kyung, Kim, Myoung Jun, Wie, Jinhong, You, Jueng Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA damage DNA methylation DNA methylome DNA replication Dynamins - metabolism gene ontology genes genomic islands Humans interphase Mdivi-1 mitochondria mitochondrial DNA Mitochondrial Dynamics Mitochondrial retrograde signaling Neuroblastoma Parkinson disease Quinazolinones - pharmacology Reactive Oxygen Species - metabolism RNA sequence analysis transcription (genetics) Transcriptome Tumor Suppressor Protein p53 - genetics
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