Variants in FOXC1 and FOXC2 identified in patients with conotruncal heart defects

Conotruncal heart defects (CTD), subtypes of congenital heart disease, result from abnormal cardiac outflow tract development (OFT). FOXC1 and FOXC2 are closely related members of the forkhead transcription factor family and play essential roles in the development of OFT. We confirmed their expressi...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 2024-05, Vol.116 (3), p.110840, Article 110840
Hauptverfasser:	Wei, Wei, Li, Bojian, Li, Fen, Sun, Kun, Jiang, Xuechao, Xu, Rang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Conotruncal heart defects Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism FOXC1 FOXC2 Heart Defects, Congenital - genetics Heart Defects, Congenital - metabolism Humans Mice T-Box Domain Proteins - genetics T-Box Domain Proteins - metabolism TBX1 Variants
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