Integrative analyses of whole-transcriptome sequencing reveals CeRNA regulatory network in pulmonary hypertension treated with FGF21

•Whole-transcriptome sequencing reveals the FGF21-regulated-ceRNA network in PH.•MiR-7a-5p, miR-449c-5p, miR-676-3p and miR-674-3p is the core of ceRNA network.•MAPK pathway and epigenetic modification involved in the anti-PH effects of FGF21.•This study provides potential biomarkers for the applica...

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Veröffentlicht in:	International immunopharmacology 2024-05, Vol.132, p.111925, Article 111925
Hauptverfasser:	Li, Xiuchun, Song, Lanlan, Lu, Ziyi, Tong, Shuolan, Zhang, Chi, Zhang, Yaxin, Wang, Xinghong, Cai, Haijian, Zhang, Jianhao, Lin, Jin, Wang, Liangxing, Wang, Jian, Huang, Xiaoying
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics analysis competing endogenous RNA noncoding RNA Pulmonary hypertension RNA sequencing
Online-Zugang:	Volltext
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