The Effect of Lipid Composition on the Liposomal Delivery of Camptothecin Developed by Active Click Loading

In the present study, we investigated the role of lipid composition of camptothecin (CPT)-loaded liposomes (CPT-Lips) to adjust their residence time, drug distribution, and therefore the toxicities and antitumor activity. The CPT was loaded into liposomes using a click drug loading method, which uti...

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Veröffentlicht in:Molecular pharmaceutics 2024-05, Vol.21 (5), p.2327-2339
Hauptverfasser: Xie, Lei, Zhang, Qian, Zhu, Qian, Wang, Yang, Niu, Shuijiao, Zhang, Xinyue, Huang, Yuting, Li, Jiayao, Liu, Xiaoxue, Xue, Zhiyuan, Zhao, Xia, Zheng, Yaxin
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Sprache:eng
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