Validation of tag SNPs for multiple sclerosis HLA risk alleles across the 1000 genomes panel

Currently, the genetic variants strongly associated with risk for Multiple Sclerosis (MS) are located in the Major Histocompatibility Complex. This includes DRB1*15:01 and DRB1*15:03 alleles at the HLA-DRB1 locus, the latter restricted to African populations; the DQB1*06:02 allele at the HLA-DQB1 lo...

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Veröffentlicht in:	Human immunology 2024-05, Vol.85 (3), p.110790-110790, Article 110790
Hauptverfasser:	Boullerne, Anne I., Goudey, Benjamin, Paganini, Julien, Erlichster, Michael, Gaitonde, Sujata, Feinstein, Douglas L.
Format:	Artikel
Sprache:	eng
Schlagworte:	1000 genomes HLA MHC Multiple sclerosis Single nucleotide polymorphism
Online-Zugang:	Volltext
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