Loureirin B ameliorates cholestatic liver fibrosis via AKT/mTOR/ATG7-mediated autophagy of hepatic stellate cells

Chronic cholestasis leads to liver fibrosis, which lacks effective treatment. In this study, we investigated the role and mechanisms of action of loureirin B (LB) in cholestatic liver fibrosis. Bile duct ligation (BDL)-induced hepatic fibrosis mice were used as in vivo models. Transforming growth fa...

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Veröffentlicht in:	European journal of pharmacology 2024-05, Vol.971, p.176552-176552, Article 176552
Hauptverfasser:	Cheng, Wei-yi, Zeng, Xi-xi, Cheng, Ping, Zhang, Jin-xiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Autophagy Hepatic stellate cells Liver fibrosis Loureirin B
Online-Zugang:	Volltext
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