Spatially modulated ablation driven by chaotic attractors in human lung epithelial cancer cells
A significant modification in photoinduced energy transfer in cancer cells is reported by the assistance of a dynamic modulation of the beam size of laser irradiation. Human lung epithelial cancer cells in monolayer form were studied. In contrast to the quantum and thermal ablation effect promoted b...
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| Veröffentlicht in: | Biomedical physics & engineering express 2024-05, Vol.10 (3), p.35041 |
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| creator | Martines-Arano, Hilario Valdivia-Flores, Alejandra Castillo-Cruz, Juan García-Pérez, Blanca Estela Torres-Torres, Carlos |
| description | A significant modification in photoinduced energy transfer in cancer cells is reported by the assistance of a dynamic modulation of the beam size of laser irradiation. Human lung epithelial cancer cells in monolayer form were studied. In contrast to the quantum and thermal ablation effect promoted by a standard focused Gaussian beam, a spatially modulated beam can caused around 15% of decrease in the ablation threshold and formation of a ring-shaped distribution of the photothermal transfer effect. Optical irradiation was conducted in A549 cells by a 532 nm single-beam emerging from a Nd:YVO4 system. Ablation effects derived from spatially modulated convergent waves were controlled by an electrically focus-tunable lens. The proposed chaotic behavior of the spatial modulation followed an Arneodo chaotic oscillator. Fractional dynamic thermal transport was analyzed in order to describe photoenergy in propagation through the samples. Immediate applications of chaos theory for developing phototechnology devices driving biological functions or phototherapy treatments can be considered. |
| doi_str_mv | 10.1088/2057-1976/ad39f1 |
| format | Article |
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Human lung epithelial cancer cells in monolayer form were studied. In contrast to the quantum and thermal ablation effect promoted by a standard focused Gaussian beam, a spatially modulated beam can caused around 15% of decrease in the ablation threshold and formation of a ring-shaped distribution of the photothermal transfer effect. Optical irradiation was conducted in A549 cells by a 532 nm single-beam emerging from a Nd:YVO4 system. Ablation effects derived from spatially modulated convergent waves were controlled by an electrically focus-tunable lens. The proposed chaotic behavior of the spatial modulation followed an Arneodo chaotic oscillator. Fractional dynamic thermal transport was analyzed in order to describe photoenergy in propagation through the samples. 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Phys. Eng. Express</addtitle><description>A significant modification in photoinduced energy transfer in cancer cells is reported by the assistance of a dynamic modulation of the beam size of laser irradiation. Human lung epithelial cancer cells in monolayer form were studied. In contrast to the quantum and thermal ablation effect promoted by a standard focused Gaussian beam, a spatially modulated beam can caused around 15% of decrease in the ablation threshold and formation of a ring-shaped distribution of the photothermal transfer effect. Optical irradiation was conducted in A549 cells by a 532 nm single-beam emerging from a Nd:YVO4 system. Ablation effects derived from spatially modulated convergent waves were controlled by an electrically focus-tunable lens. The proposed chaotic behavior of the spatial modulation followed an Arneodo chaotic oscillator. Fractional dynamic thermal transport was analyzed in order to describe photoenergy in propagation through the samples. Immediate applications of chaos theory for developing phototechnology devices driving biological functions or phototherapy treatments can be considered.</description><subject>A549 Cells</subject><subject>Cell Line, Tumor</subject><subject>chaotic arneodo system</subject><subject>Epithelial Cells - metabolism</subject><subject>Epithelial Cells - radiation effects</subject><subject>fractional calculus</subject><subject>Humans</subject><subject>Laser Therapy - methods</subject><subject>Lasers</subject><subject>lung epithelial cancer cells</subject><subject>Lung Neoplasms - pathology</subject><subject>Lung Neoplasms - radiotherapy</subject><subject>nanosecond laser ablation</subject><subject>Nonlinear Dynamics</subject><subject>photodamage</subject><subject>ring-shaped ablation</subject><issn>2057-1976</issn><issn>2057-1976</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEFP3DAQRi1EBYhy51T5yIGFcRzHybFCbUFC4gCcrYkz7holcWo7Vfffk2gB9VD1NNbofZ_Gj7FzAVcC6vq6AKU3otHVNXayceKAnXysDv96H7OzlF4AQFRFVTXqiB3LWlVNWZcnzDxOmD32_Y4PoZt7zNRxbJfpw8i76H_TyNsdt1sM2VuOOUe0OcTE_ci384Aj7-fxJ6fJ5y31SxW3OFqK3FLfp8_sk8M-0dnbPGXP37893dxu7h9-3N18vd_YUoi8UU47qLum1laLoi4IStRQa-0aslBUjkBhQcraUkstSRXQFkC2QuGwRS1P2cW-d4rh10wpm8Gn9QIcKczJSJASoJGNWlDYozaGlCI5M0U_YNwZAWY1a1Z1ZlVn9maXyJe39rkdqPsIvHtcgMs94MNkXsIcx-Wz_-u7-AfeTvRnzUgDUkEpzNQ5-QqBz5By</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Martines-Arano, Hilario</creator><creator>Valdivia-Flores, Alejandra</creator><creator>Castillo-Cruz, Juan</creator><creator>García-Pérez, Blanca Estela</creator><creator>Torres-Torres, Carlos</creator><general>IOP Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9255-2416</orcidid><orcidid>https://orcid.org/0000-0001-6129-7352</orcidid></search><sort><creationdate>20240501</creationdate><title>Spatially modulated ablation driven by chaotic attractors in human lung epithelial cancer cells</title><author>Martines-Arano, Hilario ; Valdivia-Flores, Alejandra ; Castillo-Cruz, Juan ; García-Pérez, Blanca Estela ; Torres-Torres, Carlos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c411t-5f7f08d987c71282e04a70877f9ec026fe05a2e5cc47373e520b20ec6a1faba73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>A549 Cells</topic><topic>Cell Line, Tumor</topic><topic>chaotic arneodo system</topic><topic>Epithelial Cells - metabolism</topic><topic>Epithelial Cells - radiation effects</topic><topic>fractional calculus</topic><topic>Humans</topic><topic>Laser Therapy - methods</topic><topic>Lasers</topic><topic>lung epithelial cancer cells</topic><topic>Lung Neoplasms - pathology</topic><topic>Lung Neoplasms - radiotherapy</topic><topic>nanosecond laser ablation</topic><topic>Nonlinear Dynamics</topic><topic>photodamage</topic><topic>ring-shaped ablation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martines-Arano, Hilario</creatorcontrib><creatorcontrib>Valdivia-Flores, Alejandra</creatorcontrib><creatorcontrib>Castillo-Cruz, Juan</creatorcontrib><creatorcontrib>García-Pérez, Blanca Estela</creatorcontrib><creatorcontrib>Torres-Torres, Carlos</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biomedical physics & engineering express</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martines-Arano, Hilario</au><au>Valdivia-Flores, Alejandra</au><au>Castillo-Cruz, Juan</au><au>García-Pérez, Blanca Estela</au><au>Torres-Torres, Carlos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Spatially modulated ablation driven by chaotic attractors in human lung epithelial cancer cells</atitle><jtitle>Biomedical physics & engineering express</jtitle><stitle>BPEX</stitle><addtitle>Biomed. 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| subjects | A549 Cells Cell Line, Tumor chaotic arneodo system Epithelial Cells - metabolism Epithelial Cells - radiation effects fractional calculus Humans Laser Therapy - methods Lasers lung epithelial cancer cells Lung Neoplasms - pathology Lung Neoplasms - radiotherapy nanosecond laser ablation Nonlinear Dynamics photodamage ring-shaped ablation |
| title | Spatially modulated ablation driven by chaotic attractors in human lung epithelial cancer cells |
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