The covariance environment defines cellular niches for spatial inference

A key challenge of analyzing data from high-resolution spatial profiling technologies is to suitably represent the features of cellular neighborhoods or niches. Here we introduce the covariance environment (COVET), a representation that leverages the gene-gene covariate structure across cells in the...

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Veröffentlicht in:	Nature biotechnology 2024-04
Hauptverfasser:	Haviv, Doron, Remšík, Ján, Gatie, Mohamed, Snopkowski, Catherine, Takizawa, Meril, Pereira, Nathan, Bashkin, John, Jovanovich, Stevan, Nawy, Tal, Chaligne, Ronan, Boire, Adrienne, Hadjantonakis, Anna-Katerina, Pe'er, Dana
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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