Impact of cesarean scar defect on reproductive outcomes after assisted reproductive technology

In the last twenty years, the cesarean section rate has been rising in China, leading to an increased prevalence of cesarean scar defect (CSD) and secondary infertility. CSD decreases receptivity of endometrium, induces adenomyosis and endometriosis, disrupts uterine micro-environment and causes dif...

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Veröffentlicht in:Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban 2024-03, Vol.53 (3), p.313-320
Hauptverfasser: Wang, Ling, Zhao, Chenhan, Zhang, Qin
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Zhao, Chenhan
Zhang, Qin
description In the last twenty years, the cesarean section rate has been rising in China, leading to an increased prevalence of cesarean scar defect (CSD) and secondary infertility. CSD decreases receptivity of endometrium, induces adenomyosis and endometriosis, disrupts uterine micro-environment and causes difficulties in embryo transplant operation as well as has further pregnancy complications. For women undergoing assisted reproductive technology (ART), CSD significantly reduces live birth rate, clinical pregnancy rate and embryo implantation rate. CSD can be effectively treated by hysteroscopic surgery, laparoscopic surgery and transvaginal surgery to increase the pregnancy rate. This article reviews the research progress on the impact of CSD on the reproductive outcomes of ART, the potential factors and related treatments, and provides a reference for the management of CSD patients undergoing ART.
doi_str_mv 10.3724/zdxbyxb-2023-0539
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subjects Cesarean Section - adverse effects
Cicatrix - complications
Cicatrix - etiology
Female
Humans
Infertility, Female - etiology
Pregnancy
Pregnancy Outcome
Pregnancy Rate
Reproductive Techniques, Assisted - adverse effects
title Impact of cesarean scar defect on reproductive outcomes after assisted reproductive technology
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