FGF21 protects against ischaemia reperfusion injury in normal and fatty livers

Background Liver ischaemia/reperfusion (I/R) injury, which is an inevitable clinical problem of liver resection, liver transplantation and haemorrhagic shock. Fibroblast growth factor 21 (FGF21) was intimately coupled with multiple metabolic processes and proved to protect against apoptosis and infl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Liver international 2024-07, Vol.44 (7), p.1668-1679
Hauptverfasser:	Ma, Yong, Singhal, Garima, Chan, Suzanne S., Wang, Chaoqun, Yu, Hongjun, Yin, Bing, Pang, Jing, Malvar, Grace, Nasser, Imad, Mather, Marie L., Maratos‐Flier, Eleftheria
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Diet Disease Models, Animal Fatty Liver - genetics Fatty Liver - pathology Female fibroblast growth factor 21 Fibroblast Growth Factors - genetics Fibroblast Growth Factors - metabolism Growth factors Hemangioma Hepatectomy Hepatocytes Hepatocytes - metabolism Hepatocytes - pathology High fat diet Humans Inflammation Inflammatory response Injuries injury ischaemia/reperfusion Ischemia Ketogenesis Liver Liver - metabolism Liver - pathology Liver transplantation Low carbohydrate diet Male Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Regulatory mechanisms (biology) Reperfusion Reperfusion Injury - metabolism Reperfusion Injury - pathology Reperfusion Injury - prevention & control Serum levels Therapeutic targets Transgenic mice
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!