USP40 promotes hepatocellular carcinoma progression through a YAP/USP40 positive feedback loop

Yes-associated protein (YAP) is an essential driver of hepatocellular carcinoma (HCC) progression and the ubiquitin-proteasome system controls its abundance. However, the role of ubiquitin-specific protease 40 (USP40) in YAP stability remains unclear. Here, USP40 was first identified as a novel regu...

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Veröffentlicht in:	Cancer letters 2024-05, Vol.589, p.216832-216832, Article 216832
Hauptverfasser:	Mo, Huanye, Li, Runtian, Yang, Nan, Han, Jiaqi, Xiao, Xuelian, Zhang, Yilei, Xiao, Zhengtao, Jiao, Lianying, Xu, Qiuran, Tu, Kangsheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Hepatocellular carcinoma Stiffness Tumor progression USP40 YAP
Online-Zugang:	Volltext
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