The adverse effects of fine particle air pollution on respiratory function in the elderly
There is increasing concern that airborne particles are critical risk factors for adverse health conditions in susceptible populations. The objective of this panel study is to investigate an association between particulate matter and the peak expiratory flow rate (PEFR) in the elderly and to compare...
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| Veröffentlicht in: | The Science of the total environment 2007-10, Vol.385 (1), p.28-36 |
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| creator | Lee, Jong-Tae Son, Ji-Young Cho, Yong-Sung |
| description | There is increasing concern that airborne particles are critical risk factors for adverse health conditions in susceptible populations. The objective of this panel study is to investigate an association between particulate matter and the peak expiratory flow rate (PEFR) in the elderly and to compare estimated risks using PM
10 or PM
2.5 levels as a measure of exposure. During a 2-year longitudinal follow-up study, we contacted subjects living in an asylum for the elderly, provided them with a mini-Wright peak flow meter, and instructed to record all the flow readings, any respiratory symptoms, passive smoking activity, and hours spent outdoors for that given day. Daily levels of particulate matter were measured by two separate mini-volume air samplers (for PM
10 and PM
2.5) placed on the rooftop of the two-story residence asylum building. In our statistical models, we assumed that the expected response varied linearly for each participant with a slope and intercept that depended on fixed or time-varying covariates using a mixed linear model. The daily mean levels of PM
10 and PM
2.5 were 78 μg/m
3 and 56 μg/m
3, respectively. For every 10 μg/m
3 increase in PM
10 and PM
2.5 levels, there was an estimated PEFR change of −
0.39 l/min (95% CI, −
0.63, −
0.14) and −
0.54 l/min (95% CI, −
0.89, −
0.19), respectively. These data also suggest that fine particles have a more adverse respiratory health impact for sensitive individuals such as the elderly and that more research and control strategies should focus on the smaller particles associated with air pollution. |
| doi_str_mv | 10.1016/j.scitotenv.2007.07.005 |
| format | Article |
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10 or PM
2.5 levels as a measure of exposure. During a 2-year longitudinal follow-up study, we contacted subjects living in an asylum for the elderly, provided them with a mini-Wright peak flow meter, and instructed to record all the flow readings, any respiratory symptoms, passive smoking activity, and hours spent outdoors for that given day. Daily levels of particulate matter were measured by two separate mini-volume air samplers (for PM
10 and PM
2.5) placed on the rooftop of the two-story residence asylum building. In our statistical models, we assumed that the expected response varied linearly for each participant with a slope and intercept that depended on fixed or time-varying covariates using a mixed linear model. The daily mean levels of PM
10 and PM
2.5 were 78 μg/m
3 and 56 μg/m
3, respectively. For every 10 μg/m
3 increase in PM
10 and PM
2.5 levels, there was an estimated PEFR change of −
0.39 l/min (95% CI, −
0.63, −
0.14) and −
0.54 l/min (95% CI, −
0.89, −
0.19), respectively. These data also suggest that fine particles have a more adverse respiratory health impact for sensitive individuals such as the elderly and that more research and control strategies should focus on the smaller particles associated with air pollution.</description><identifier>ISSN: 0048-9697</identifier><identifier>EISSN: 1879-1026</identifier><identifier>DOI: 10.1016/j.scitotenv.2007.07.005</identifier><identifier>PMID: 17692897</identifier><identifier>CODEN: STENDL</identifier><language>eng</language><publisher>Shannon: Elsevier B.V</publisher><subject>Aged ; Air ; Air pollution ; Air Pollution - adverse effects ; Biological and medical sciences ; Environment. Living conditions ; Environmental Monitoring ; Environmental pollutants toxicology ; Female ; Fine particle ; Humans ; Korea ; Longitudinal Studies ; Male ; Medical sciences ; Mixed linear model ; Particle Size ; Particulate Matter - toxicity ; Peak Expiratory Flow Rate - drug effects ; PEFR ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Respiration - drug effects ; The elderly ; Toxicology</subject><ispartof>The Science of the total environment, 2007-10, Vol.385 (1), p.28-36</ispartof><rights>2007 Elsevier B.V.</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c558t-b74ea3043a83dbedd1087e60c1a64ec6c97ebee3879a0910ae91e7c3764f8fa03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0048969707007553$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19101891$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17692897$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lee, Jong-Tae</creatorcontrib><creatorcontrib>Son, Ji-Young</creatorcontrib><creatorcontrib>Cho, Yong-Sung</creatorcontrib><title>The adverse effects of fine particle air pollution on respiratory function in the elderly</title><title>The Science of the total environment</title><addtitle>Sci Total Environ</addtitle><description>There is increasing concern that airborne particles are critical risk factors for adverse health conditions in susceptible populations. The objective of this panel study is to investigate an association between particulate matter and the peak expiratory flow rate (PEFR) in the elderly and to compare estimated risks using PM
10 or PM
2.5 levels as a measure of exposure. During a 2-year longitudinal follow-up study, we contacted subjects living in an asylum for the elderly, provided them with a mini-Wright peak flow meter, and instructed to record all the flow readings, any respiratory symptoms, passive smoking activity, and hours spent outdoors for that given day. Daily levels of particulate matter were measured by two separate mini-volume air samplers (for PM
10 and PM
2.5) placed on the rooftop of the two-story residence asylum building. In our statistical models, we assumed that the expected response varied linearly for each participant with a slope and intercept that depended on fixed or time-varying covariates using a mixed linear model. The daily mean levels of PM
10 and PM
2.5 were 78 μg/m
3 and 56 μg/m
3, respectively. For every 10 μg/m
3 increase in PM
10 and PM
2.5 levels, there was an estimated PEFR change of −
0.39 l/min (95% CI, −
0.63, −
0.14) and −
0.54 l/min (95% CI, −
0.89, −
0.19), respectively. These data also suggest that fine particles have a more adverse respiratory health impact for sensitive individuals such as the elderly and that more research and control strategies should focus on the smaller particles associated with air pollution.</description><subject>Aged</subject><subject>Air</subject><subject>Air pollution</subject><subject>Air Pollution - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Environment. Living conditions</subject><subject>Environmental Monitoring</subject><subject>Environmental pollutants toxicology</subject><subject>Female</subject><subject>Fine particle</subject><subject>Humans</subject><subject>Korea</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mixed linear model</subject><subject>Particle Size</subject><subject>Particulate Matter - toxicity</subject><subject>Peak Expiratory Flow Rate - drug effects</subject><subject>PEFR</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Respiration - drug effects</subject><subject>The elderly</subject><subject>Toxicology</subject><issn>0048-9697</issn><issn>1879-1026</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2LFDEQhoMo7rj6FzQXvfVY6XTn47gs6wcseFkPnkImXcEMmU6bdA_MvzftDO5xihcKwlMfqZeQDwy2DJj4vN8WF-Y043jctgByuwr6F2TDlNQNg1a8JBuATjVaaHlD3pSyhxpSsdfkhkmhW6Xlhvx6-o3UDkfMBSl6j24uNHnqw4h0snkOLlYgZDqlGJc5pJFWZSxTyHZO-UT9Mrp_72Gkc-2GccAcT2_JK29jwXeXfEt-fnl4uv_WPP74-v3-7rFxfa_mZic7tBw6bhUfdjgMDJREAY5Z0aETTkvcIfL6LQuagUXNUDouReeVt8Bvyadz3ymnPwuW2RxCcRijHTEtxXBgvOMtvwoyLZXoVXsd7NTK6grKM-hyKiWjN1MOB5tPhoFZfTJ7898ns_pkVkFfK99fRiy7Aw7PdRdjKvDxAtjibPTZji6UZ65eginNKnd35rCe-BgwrwNxdDiEXL00QwpXl_kLwp62rw</recordid><startdate>20071015</startdate><enddate>20071015</enddate><creator>Lee, Jong-Tae</creator><creator>Son, Ji-Young</creator><creator>Cho, Yong-Sung</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>7T2</scope><scope>7TG</scope><scope>7TV</scope><scope>7U1</scope><scope>7U2</scope><scope>7U7</scope><scope>KL.</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope></search><sort><creationdate>20071015</creationdate><title>The adverse effects of fine particle air pollution on respiratory function in the elderly</title><author>Lee, Jong-Tae ; Son, Ji-Young ; Cho, Yong-Sung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c558t-b74ea3043a83dbedd1087e60c1a64ec6c97ebee3879a0910ae91e7c3764f8fa03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Aged</topic><topic>Air</topic><topic>Air pollution</topic><topic>Air Pollution - adverse effects</topic><topic>Biological and medical sciences</topic><topic>Environment. Living conditions</topic><topic>Environmental Monitoring</topic><topic>Environmental pollutants toxicology</topic><topic>Female</topic><topic>Fine particle</topic><topic>Humans</topic><topic>Korea</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mixed linear model</topic><topic>Particle Size</topic><topic>Particulate Matter - toxicity</topic><topic>Peak Expiratory Flow Rate - drug effects</topic><topic>PEFR</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Respiration - drug effects</topic><topic>The elderly</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lee, Jong-Tae</creatorcontrib><creatorcontrib>Son, Ji-Young</creatorcontrib><creatorcontrib>Cho, Yong-Sung</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Pollution Abstracts</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><jtitle>The Science of the total environment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lee, Jong-Tae</au><au>Son, Ji-Young</au><au>Cho, Yong-Sung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The adverse effects of fine particle air pollution on respiratory function in the elderly</atitle><jtitle>The Science of the total environment</jtitle><addtitle>Sci Total Environ</addtitle><date>2007-10-15</date><risdate>2007</risdate><volume>385</volume><issue>1</issue><spage>28</spage><epage>36</epage><pages>28-36</pages><issn>0048-9697</issn><eissn>1879-1026</eissn><coden>STENDL</coden><abstract>There is increasing concern that airborne particles are critical risk factors for adverse health conditions in susceptible populations. The objective of this panel study is to investigate an association between particulate matter and the peak expiratory flow rate (PEFR) in the elderly and to compare estimated risks using PM
10 or PM
2.5 levels as a measure of exposure. During a 2-year longitudinal follow-up study, we contacted subjects living in an asylum for the elderly, provided them with a mini-Wright peak flow meter, and instructed to record all the flow readings, any respiratory symptoms, passive smoking activity, and hours spent outdoors for that given day. Daily levels of particulate matter were measured by two separate mini-volume air samplers (for PM
10 and PM
2.5) placed on the rooftop of the two-story residence asylum building. In our statistical models, we assumed that the expected response varied linearly for each participant with a slope and intercept that depended on fixed or time-varying covariates using a mixed linear model. The daily mean levels of PM
10 and PM
2.5 were 78 μg/m
3 and 56 μg/m
3, respectively. For every 10 μg/m
3 increase in PM
10 and PM
2.5 levels, there was an estimated PEFR change of −
0.39 l/min (95% CI, −
0.63, −
0.14) and −
0.54 l/min (95% CI, −
0.89, −
0.19), respectively. These data also suggest that fine particles have a more adverse respiratory health impact for sensitive individuals such as the elderly and that more research and control strategies should focus on the smaller particles associated with air pollution.</abstract><cop>Shannon</cop><pub>Elsevier B.V</pub><pmid>17692897</pmid><doi>10.1016/j.scitotenv.2007.07.005</doi><tpages>9</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Aged Air Air pollution Air Pollution - adverse effects Biological and medical sciences Environment. Living conditions Environmental Monitoring Environmental pollutants toxicology Female Fine particle Humans Korea Longitudinal Studies Male Medical sciences Mixed linear model Particle Size Particulate Matter - toxicity Peak Expiratory Flow Rate - drug effects PEFR Public health. Hygiene Public health. Hygiene-occupational medicine Respiration - drug effects The elderly Toxicology |
| title | The adverse effects of fine particle air pollution on respiratory function in the elderly |
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