Soluble Borate Glasses: In Vitro Analysis

In vitro bioactivity of borate glasses with composition xNa2O·xCaO·2xB2O3 (where x is in wt%=24.8, 24.2, 23.8, 23.2) containing 0, 2, 4, 6 wt% P2O5 has been investigated by soaking them in a simulating body fluid (SBF) up to 15 days at 37°C. Investigation of glass degradation is carried out by takin...

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Veröffentlicht in:Journal of the American Ceramic Society 2007-02, Vol.90 (2), p.467-471
Hauptverfasser: Thind, Kulwant Singh, Sharma, Gopi, Singh, Kulvir, Rajendran, Venkatachalam, Aravindan, Sayinckaniayn
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container_end_page 471
container_issue 2
container_start_page 467
container_title Journal of the American Ceramic Society
container_volume 90
creator Thind, Kulwant Singh
Sharma, Gopi
Singh, Kulvir
Rajendran, Venkatachalam
Aravindan, Sayinckaniayn
description In vitro bioactivity of borate glasses with composition xNa2O·xCaO·2xB2O3 (where x is in wt%=24.8, 24.2, 23.8, 23.2) containing 0, 2, 4, 6 wt% P2O5 has been investigated by soaking them in a simulating body fluid (SBF) up to 15 days at 37°C. Investigation of glass degradation is carried out by taking percentage weight loss in SBF and by measuring the pH of SBF as a function of time. Inductively coupled plasma emission spectroscopy is used to study the ionic concentration of BIII, CaII, and NaI ions in SBF after 15 days of assay. Fourier transform infrared spectra are taken before and after dipping in SBF for structural analysis and for confirmation of hydroxyl carbonate apatite layer formation in SBF after 15 days. The results show that P2O5 plays an important role in controlling chemical durability and bioactivity. A borate glass with the same composition as 45S5 bioglass prepared by Hench but with SiO2 replaced by B2O3 in weight percentage has been prepared for comparison of bioactivity for the two.
doi_str_mv 10.1111/j.1551-2916.2006.01449.x
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source Wiley Online Library Journals Frontfile Complete
subjects Applied sciences
Building materials. Ceramics. Glasses
Chemical compounds
Chemical industry and chemicals
Chemistry
Exact sciences and technology
Glasses
Ions
Structure, analysis, properties
title Soluble Borate Glasses: In Vitro Analysis
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