R-tPA Resistance Is Specific for Platelet-Rich Stroke Thrombi and Can Be Overcome by Targeting Nonfibrin Components

Resistance to r-tPA (recombinant tissue-type plasminogen activator) is a well-known but poorly understood phenomenon that hampers successful recanalization in patients with acute ischemic stroke. Using clinically relevant thrombi from patients with acute ischemic stroke, we investigated if and how t...

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Veröffentlicht in:	Stroke (1970) 2024-05, Vol.55 (5), p.1181-1190
Hauptverfasser:	Vandelanotte, Sarah, François, Olivier, Desender, Linda, Staessens, Senna, Vanhoorne, Alexander, Van Gool, Fréderick, Tersteeg, Claudia, Vanhoorelbeke, Karen, Vanacker, Peter, Andersson, Tommy, De Meyer, Simon F
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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