Antiproliferative activities through accelerating autophagic flux by basidalin and its analogs in human cancer cells

[Display omitted] Basidalin, isolated from the basidiomycete Leucoagaricus naucina, has previously demonstrated antibacterial and antitumor properties against murine cancer cells in vivo, but its effects on human cancer cells remain unknown. In this study, we found that basidalin possesses antiproli...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2024-05, Vol.104, p.129713-129713, Article 129713
Hauptverfasser:	Matagawa, Tomoe, Sasazawa, Yukiko, Agui, Koki, Fujimaki, Motoki, Kawano, Sayaka, Ogura, Akihiro, Takao, Ken-ichi, Igarashi, Masayuki, Simizu, Siro
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic Antiproliferative activity Autophagy inducer Basidalin mTOR signal Structure–activity relationship
Online-Zugang:	Volltext
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