Neurobehavioral and Respiratory Findings in Jet Engine Repair Workers: A Comparison of Exposed and Unexposed Volunteers
Workers repairing jet engines had respiratory, rheumatic, and neurobehavioral symptoms. They had welded and ground stainless steel parts using hard metal tools and cleaned metal with chlorinated and fluorinated organic solvents. We compared 154 workers and 112 unexposed subjects, all volunteers of s...
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| Veröffentlicht in: | Environmental research 1999-04, Vol.80 (3), p.244-252 |
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| creator | Kilburn, Kaye H. |
| description | Workers repairing jet engines had respiratory, rheumatic, and neurobehavioral symptoms. They had welded and ground stainless steel parts using hard metal tools and cleaned metal with chlorinated and fluorinated organic solvents. We compared 154 workers and 112 unexposed subjects, all volunteers of similar ages and with similar educational levels, for abnormalities on chest radiographs, spirometric measurements, and questionnaires. Also appraised were performance of reaction time, balance, blink reflex latency, color discrimination, Culture Fair, vocabulary, slotted pegboard, trail making A and B, profile of mood states (POMS), and frequencies of 35 symptoms. Compared to unexposed subjects, workers had significantly more respiratory symptoms but no differences in pulmonary function. They had significantly prolonged simple and choice reaction time (P |
| doi_str_mv | 10.1006/enrs.1998.3898 |
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They had welded and ground stainless steel parts using hard metal tools and cleaned metal with chlorinated and fluorinated organic solvents. We compared 154 workers and 112 unexposed subjects, all volunteers of similar ages and with similar educational levels, for abnormalities on chest radiographs, spirometric measurements, and questionnaires. Also appraised were performance of reaction time, balance, blink reflex latency, color discrimination, Culture Fair, vocabulary, slotted pegboard, trail making A and B, profile of mood states (POMS), and frequencies of 35 symptoms. Compared to unexposed subjects, workers had significantly more respiratory symptoms but no differences in pulmonary function. They had significantly prolonged simple and choice reaction time (P<0.0001), and abnormal balance with eyes open and eyes closed (P<0.0001), and abnormal color discrimination. Blink reflex latency was abnormal in both exposed workers and in local unexposed compared to other reference groups. Focus of the inquiry on lung disease helped ensure that for neurobehavioral tests confounding factors were minimal and known biases were small. We tentatively attribute the neurobehavioral impairments and increased symptom frequencies to chlorinated solvent exposure. Excessive respiratory symptoms are attributed to welding stainless steel combined with cigarette smoking. Specifically, manganese exposure may have affected the respiratory and the central nervous systems.</description><identifier>ISSN: 0013-9351</identifier><identifier>EISSN: 1096-0953</identifier><identifier>DOI: 10.1006/enrs.1998.3898</identifier><identifier>PMID: 10092444</identifier><identifier>CODEN: ENVRAL</identifier><language>eng</language><publisher>Amsterdam: Elsevier Inc</publisher><subject>1,1,1-trichloroethane-chlorinated solvents ; Adult ; Aircraft ; balance ; Biological and medical sciences ; blink ; Blinking ; Bronchitis - diagnostic imaging ; Bronchitis - etiology ; Chemical and industrial products toxicology. Toxic occupational diseases ; Chronic Disease ; Dust - adverse effects ; Female ; Humans ; Male ; Medical sciences ; Occupational Exposure - adverse effects ; Oklahoma ; Perception ; Radiography ; Reaction Time ; Respiratory Function Tests ; Smoking ; Solvents ; Solvents - adverse effects ; Stainless Steel - adverse effects ; Surveys and Questionnaires ; Toxicology ; trichloroethylene ; Welding</subject><ispartof>Environmental research, 1999-04, Vol.80 (3), p.244-252</ispartof><rights>1999 Academic Press</rights><rights>1999 INIST-CNRS</rights><rights>Copyright 1999 Academic Press.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c493t-cd115d259731a9032e288bd0235ecbc9b9f17491a3161d3ae8e4862b9c43c843</citedby><cites>FETCH-LOGICAL-c493t-cd115d259731a9032e288bd0235ecbc9b9f17491a3161d3ae8e4862b9c43c843</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1006/enrs.1998.3898$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1741354$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10092444$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kilburn, Kaye H.</creatorcontrib><title>Neurobehavioral and Respiratory Findings in Jet Engine Repair Workers: A Comparison of Exposed and Unexposed Volunteers</title><title>Environmental research</title><addtitle>Environ Res</addtitle><description>Workers repairing jet engines had respiratory, rheumatic, and neurobehavioral symptoms. They had welded and ground stainless steel parts using hard metal tools and cleaned metal with chlorinated and fluorinated organic solvents. We compared 154 workers and 112 unexposed subjects, all volunteers of similar ages and with similar educational levels, for abnormalities on chest radiographs, spirometric measurements, and questionnaires. Also appraised were performance of reaction time, balance, blink reflex latency, color discrimination, Culture Fair, vocabulary, slotted pegboard, trail making A and B, profile of mood states (POMS), and frequencies of 35 symptoms. Compared to unexposed subjects, workers had significantly more respiratory symptoms but no differences in pulmonary function. They had significantly prolonged simple and choice reaction time (P<0.0001), and abnormal balance with eyes open and eyes closed (P<0.0001), and abnormal color discrimination. Blink reflex latency was abnormal in both exposed workers and in local unexposed compared to other reference groups. Focus of the inquiry on lung disease helped ensure that for neurobehavioral tests confounding factors were minimal and known biases were small. We tentatively attribute the neurobehavioral impairments and increased symptom frequencies to chlorinated solvent exposure. Excessive respiratory symptoms are attributed to welding stainless steel combined with cigarette smoking. Specifically, manganese exposure may have affected the respiratory and the central nervous systems.</description><subject>1,1,1-trichloroethane-chlorinated solvents</subject><subject>Adult</subject><subject>Aircraft</subject><subject>balance</subject><subject>Biological and medical sciences</subject><subject>blink</subject><subject>Blinking</subject><subject>Bronchitis - diagnostic imaging</subject><subject>Bronchitis - etiology</subject><subject>Chemical and industrial products toxicology. Toxic occupational diseases</subject><subject>Chronic Disease</subject><subject>Dust - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Occupational Exposure - adverse effects</subject><subject>Oklahoma</subject><subject>Perception</subject><subject>Radiography</subject><subject>Reaction Time</subject><subject>Respiratory Function Tests</subject><subject>Smoking</subject><subject>Solvents</subject><subject>Solvents - adverse effects</subject><subject>Stainless Steel - adverse effects</subject><subject>Surveys and Questionnaires</subject><subject>Toxicology</subject><subject>trichloroethylene</subject><subject>Welding</subject><issn>0013-9351</issn><issn>1096-0953</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1v1DAURS0EokNhyxJ5gdhl8IudxGZXjaZ8qAIJFVhajv1SDBk7tTOF_nscZiTYoLJ6utK5V086hDwFtgbG2pcYUl6DUnLNpZL3yAqYaiumGn6frBgDXinewAl5lPO3EqHh7CE5KVVVCyFW5Md73KfY41dz42MyIzXB0Y-YJ5_MHNMtPffB-XCVqQ_0Hc50G658wIJMxif6JabvmPIrekY3cTeZ5HMMNA50-3OKGd3vuU8Bj-lzHPdhxtJ4TB4MZsz45HhPyeX59nLzprr48Prt5uyiskLxubKuvOzqRnUcjGK8xlrK3rGaN2h7q3o1QCcUGA4tOG5QopBt3SsruJWCn5IXh9kpxes95lnvfLY4jiZg3GddK8lkzeE_QNHULZN3gtCBFF179yKIBrriqYDrA2hTzDnhoKfkdybdamB6kawXyXqRrBfJpfDsuLzvd-j-wg9WC_D8CJhszTgkE6zPf7hOAG8WTB4wLAJuPCadrcdg0fmEdtYu-n-98Atfv8L1</recordid><startdate>19990401</startdate><enddate>19990401</enddate><creator>Kilburn, Kaye H.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>7TK</scope><scope>7U7</scope><scope>7TB</scope><scope>8FD</scope><scope>FR3</scope><scope>H8D</scope><scope>L7M</scope></search><sort><creationdate>19990401</creationdate><title>Neurobehavioral and Respiratory Findings in Jet Engine Repair Workers: A Comparison of Exposed and Unexposed Volunteers</title><author>Kilburn, Kaye H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c493t-cd115d259731a9032e288bd0235ecbc9b9f17491a3161d3ae8e4862b9c43c843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>1,1,1-trichloroethane-chlorinated solvents</topic><topic>Adult</topic><topic>Aircraft</topic><topic>balance</topic><topic>Biological and medical sciences</topic><topic>blink</topic><topic>Blinking</topic><topic>Bronchitis - diagnostic imaging</topic><topic>Bronchitis - etiology</topic><topic>Chemical and industrial products toxicology. Toxic occupational diseases</topic><topic>Chronic Disease</topic><topic>Dust - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Occupational Exposure - adverse effects</topic><topic>Oklahoma</topic><topic>Perception</topic><topic>Radiography</topic><topic>Reaction Time</topic><topic>Respiratory Function Tests</topic><topic>Smoking</topic><topic>Solvents</topic><topic>Solvents - adverse effects</topic><topic>Stainless Steel - adverse effects</topic><topic>Surveys and Questionnaires</topic><topic>Toxicology</topic><topic>trichloroethylene</topic><topic>Welding</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kilburn, Kaye H.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Environmental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kilburn, Kaye H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurobehavioral and Respiratory Findings in Jet Engine Repair Workers: A Comparison of Exposed and Unexposed Volunteers</atitle><jtitle>Environmental research</jtitle><addtitle>Environ Res</addtitle><date>1999-04-01</date><risdate>1999</risdate><volume>80</volume><issue>3</issue><spage>244</spage><epage>252</epage><pages>244-252</pages><issn>0013-9351</issn><eissn>1096-0953</eissn><coden>ENVRAL</coden><abstract>Workers repairing jet engines had respiratory, rheumatic, and neurobehavioral symptoms. They had welded and ground stainless steel parts using hard metal tools and cleaned metal with chlorinated and fluorinated organic solvents. We compared 154 workers and 112 unexposed subjects, all volunteers of similar ages and with similar educational levels, for abnormalities on chest radiographs, spirometric measurements, and questionnaires. Also appraised were performance of reaction time, balance, blink reflex latency, color discrimination, Culture Fair, vocabulary, slotted pegboard, trail making A and B, profile of mood states (POMS), and frequencies of 35 symptoms. Compared to unexposed subjects, workers had significantly more respiratory symptoms but no differences in pulmonary function. They had significantly prolonged simple and choice reaction time (P<0.0001), and abnormal balance with eyes open and eyes closed (P<0.0001), and abnormal color discrimination. Blink reflex latency was abnormal in both exposed workers and in local unexposed compared to other reference groups. Focus of the inquiry on lung disease helped ensure that for neurobehavioral tests confounding factors were minimal and known biases were small. We tentatively attribute the neurobehavioral impairments and increased symptom frequencies to chlorinated solvent exposure. Excessive respiratory symptoms are attributed to welding stainless steel combined with cigarette smoking. Specifically, manganese exposure may have affected the respiratory and the central nervous systems.</abstract><cop>Amsterdam</cop><pub>Elsevier Inc</pub><pmid>10092444</pmid><doi>10.1006/enrs.1998.3898</doi><tpages>9</tpages></addata></record> |
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| subjects | 1,1,1-trichloroethane-chlorinated solvents Adult Aircraft balance Biological and medical sciences blink Blinking Bronchitis - diagnostic imaging Bronchitis - etiology Chemical and industrial products toxicology. Toxic occupational diseases Chronic Disease Dust - adverse effects Female Humans Male Medical sciences Occupational Exposure - adverse effects Oklahoma Perception Radiography Reaction Time Respiratory Function Tests Smoking Solvents Solvents - adverse effects Stainless Steel - adverse effects Surveys and Questionnaires Toxicology trichloroethylene Welding |
| title | Neurobehavioral and Respiratory Findings in Jet Engine Repair Workers: A Comparison of Exposed and Unexposed Volunteers |
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