Primary Brain Tumor Mortality at a Petroleum Exploration and Extraction Research Facility
A cohort mortality study was conducted among 3779 employees at a petroleum exploration and extraction research facility to evaluate workplace exposures and brain tumor risk. Deaths were identified by searches against the National Death Index, Social Secunty Administration, and California state morta...
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| Veröffentlicht in: | Journal of occupational and environmental medicine 2004-03, Vol.46 (3), p.257-270 |
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| container_title | Journal of occupational and environmental medicine |
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| creator | Buffler, Patricia A. Kelsh, Michael Chapman, Pamela Wood, Susan Lau, Edmund Golembesky, Amanda Wood, Ralph Kalmes, Renee Brorby, Greg |
| description | A cohort mortality study was conducted among 3779 employees at a petroleum exploration and extraction research facility to evaluate workplace exposures and brain tumor risk. Deaths were identified by searches against the National Death Index, Social Secunty Administration, and California state mortality files. Work histones were classified by job titles, laboratory activity, and company division. Eleven brain tumor deaths were observed among the cohort (standardized mortality ratio [SMR] 1.8; 95% confidence interval = 0.9-3.2). SMR analyses for scientists, employment in laboratory work, and in the research division were not associated with an increased brain tumor SMR, whereas an increased SMR was observed for administrative and nonresearch employees. Although conclusions are limited by the small study population and lack of specific exposure data, these findings were not consistent with an occupational explanation for the observed brain tumor cluster. |
| doi_str_mv | 10.1097/01.jom.0000116816.09199.6d |
| format | Article |
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Deaths were identified by searches against the National Death Index, Social Secunty Administration, and California state mortality files. Work histones were classified by job titles, laboratory activity, and company division. Eleven brain tumor deaths were observed among the cohort (standardized mortality ratio [SMR] 1.8; 95% confidence interval = 0.9-3.2). SMR analyses for scientists, employment in laboratory work, and in the research division were not associated with an increased brain tumor SMR, whereas an increased SMR was observed for administrative and nonresearch employees. Although conclusions are limited by the small study population and lack of specific exposure data, these findings were not consistent with an occupational explanation for the observed brain tumor cluster.</description><identifier>ISSN: 1076-2752</identifier><identifier>EISSN: 1536-5948</identifier><identifier>DOI: 10.1097/01.jom.0000116816.09199.6d</identifier><identifier>PMID: 15091289</identifier><identifier>CODEN: JOEMFM</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Brain ; Brain Neoplasms - mortality ; California - epidemiology ; Cause of Death ; Cohort Studies ; Female ; Health risk assessment ; Humans ; Male ; Medical sciences ; Middle Aged ; Mortality ; Neurology ; Occupational diseases ; Occupational Diseases - mortality ; Occupational Exposure - adverse effects ; ORIGINAL ARTICLES ; Petroleum - toxicity ; Petroleum industry ; Registries ; Risk exposure ; Risk Factors ; Tumors ; Tumors of the nervous system. Phacomatoses</subject><ispartof>Journal of occupational and environmental medicine, 2004-03, Vol.46 (3), p.257-270</ispartof><rights>Copyright © 2004 American College of Occupational and Environmental Medicine</rights><rights>2004The American College of Occupational and Environmental Medicine</rights><rights>2004 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Mar 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5012-985a1d200edb2d9782c89af0094fe239a19c0d44ddf5584a3c3b98954684cd233</citedby><cites>FETCH-LOGICAL-c5012-985a1d200edb2d9782c89af0094fe239a19c0d44ddf5584a3c3b98954684cd233</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44996566$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44996566$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,780,784,803,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15602822$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15091289$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Buffler, Patricia A.</creatorcontrib><creatorcontrib>Kelsh, Michael</creatorcontrib><creatorcontrib>Chapman, Pamela</creatorcontrib><creatorcontrib>Wood, Susan</creatorcontrib><creatorcontrib>Lau, Edmund</creatorcontrib><creatorcontrib>Golembesky, Amanda</creatorcontrib><creatorcontrib>Wood, Ralph</creatorcontrib><creatorcontrib>Kalmes, Renee</creatorcontrib><creatorcontrib>Brorby, Greg</creatorcontrib><title>Primary Brain Tumor Mortality at a Petroleum Exploration and Extraction Research Facility</title><title>Journal of occupational and environmental medicine</title><addtitle>J Occup Environ Med</addtitle><description>A cohort mortality study was conducted among 3779 employees at a petroleum exploration and extraction research facility to evaluate workplace exposures and brain tumor risk. Deaths were identified by searches against the National Death Index, Social Secunty Administration, and California state mortality files. Work histones were classified by job titles, laboratory activity, and company division. Eleven brain tumor deaths were observed among the cohort (standardized mortality ratio [SMR] 1.8; 95% confidence interval = 0.9-3.2). SMR analyses for scientists, employment in laboratory work, and in the research division were not associated with an increased brain tumor SMR, whereas an increased SMR was observed for administrative and nonresearch employees. Although conclusions are limited by the small study population and lack of specific exposure data, these findings were not consistent with an occupational explanation for the observed brain tumor cluster.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Brain</subject><subject>Brain Neoplasms - mortality</subject><subject>California - epidemiology</subject><subject>Cause of Death</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Neurology</subject><subject>Occupational diseases</subject><subject>Occupational Diseases - mortality</subject><subject>Occupational Exposure - adverse effects</subject><subject>ORIGINAL ARTICLES</subject><subject>Petroleum - toxicity</subject><subject>Petroleum industry</subject><subject>Registries</subject><subject>Risk exposure</subject><subject>Risk Factors</subject><subject>Tumors</subject><subject>Tumors of the nervous system. 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| fulltext | fulltext |
| identifier | ISSN: 1076-2752 |
| ispartof | Journal of occupational and environmental medicine, 2004-03, Vol.46 (3), p.257-270 |
| issn | 1076-2752 1536-5948 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete; JSTOR Archive Collection A-Z Listing |
| subjects | Adult Aged Biological and medical sciences Brain Brain Neoplasms - mortality California - epidemiology Cause of Death Cohort Studies Female Health risk assessment Humans Male Medical sciences Middle Aged Mortality Neurology Occupational diseases Occupational Diseases - mortality Occupational Exposure - adverse effects ORIGINAL ARTICLES Petroleum - toxicity Petroleum industry Registries Risk exposure Risk Factors Tumors Tumors of the nervous system. Phacomatoses |
| title | Primary Brain Tumor Mortality at a Petroleum Exploration and Extraction Research Facility |
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