No Biologically Significant Changes in Liver Function After Occupational Exposure to Toluene at Over-OEL Levels

In the present study, effects of occupational exposure to toluene were examined in female workers in narrow range of ages. The findings in toluene exposed workers are presented as an entire group and also after division into two subgroups, one below the OEL of 100 ppm and the other above the OEL. The comparison by t-test between the toluene-exposed workers and control workers disclosed that ASAT, CHE, LAP and total bilirubin were lower and gamma-GTP was higher in the toluene group. Thus, it was considered possible that elevation in gamma-GTP and reduction in CHE may carry clinical significance.