Cobra (Naja naja) venom L-amino acid oxidase (NNLAAO70) induces apoptosis and secondary necrosis in human lung epithelial cancer cells

Snake venom L-amino acid oxidases (LAAOs) are flavoenzymes with diverse physiological and pharmacological effects. These enzymes are found to showcase anticoagulant, antiplatelet, cytotoxicity and other biological effects in bite victims. However, the exact mechanism through which they exhibit sever...

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Veröffentlicht in:	Journal of biosciences 2024-06, Vol.49 (2), p.43-43, Article 43
Hauptverfasser:	Rayapati, Ananda Murali, Vemulapati, Bhadramurthy, Chanda, Chandrasekhar
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Adenosine diphosphate ADP Aggregation Amino acid oxidase Amino acids Animals antibacterial properties anticoagulants Apoptosis Bacillus megaterium Bacillus subtilis Bactericidal activity Biological effects Biological properties Biological stress Biomedical and Life Sciences Biomedicine Cancer Cell Biology Cell injury Cells cobra venoms Collagen Collagen - pharmacology Cytotoxicity Deamination DNA fragmentation dose response E coli Elapid Venoms - pharmacology Elapidae epithelium Escherichia coli Humans Hydrogen peroxide Hydrogen Peroxide - pharmacology L-Amino Acid Oxidase - chemistry L-Amino Acid Oxidase - genetics L-Amino Acid Oxidase - pharmacology L-amino-acid oxidase Life Sciences Lung Lung cancer lungs Microbiology Molecular weight Naja naja Necrosis Neoplasms Oxidative stress Phosphates Physiological effects Plant Sciences Platelet aggregation Pseudomonas fluorescens Reactive oxygen species Specificity Substrate specificity Substrates Toxicity Venom viability Water purification Zoology
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