Diagnosing and Treating Blastic Plasmacytoid Dendritic Cell Neoplasm in a Resource-Limited Setting
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematological malignancy with limited treatment options and poor prognosis. This case report presents the clinical course and management of a 62-year-old man with BPDCN in a resource-limited setting. The patient presented...
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| Veröffentlicht in: | Oncology (Williston Park, N.Y.) N.Y.), 2024-03, Vol.38 (3), p.104-106 |
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| container_title | Oncology (Williston Park, N.Y.) |
| container_volume | 38 |
| creator | Khan, Fiza Hashmi, Foorquan Ghahramanyan, Nerses Baloyan, Elen Tamamyan, Gevorg Konopleva, Marina Pemmaraju, Naveen Voskanyan, Astghik |
| description | Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematological malignancy with limited treatment options and poor prognosis. This case report presents the clinical course and management of a 62-year-old man with BPDCN in a resource-limited setting. The patient presented with constitutional symptoms and abnormal complete blood count findings. Initial treatment was performed with an acute lymphoblastic leukemia-based chemotherapy regimen, and the patient achieved complete remission, but the disease recurred 7 months after the initial diagnosis was confirmed in April 2022. The subsequent therapy was not effective, and the patient died during treatment. This case highlights the challenges in managing BPDCN and the need for further research to improve outcomes. |
| doi_str_mv | 10.46883/2024.25921014 |
| format | Article |
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| ispartof | Oncology (Williston Park, N.Y.), 2024-03, Vol.38 (3), p.104-106 |
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| subjects | Abdomen Antimitotic agents Antineoplastic agents Blood Blood tests Bone marrow Cancer Care and treatment Case reports Chemotherapy Dendritic Cells Development and progression Diagnosis Flow cytometry Hematologic Neoplasms - therapy Hematology Humans Induction therapy Leukemia Lymphatic system Male Medical diagnosis Medical examination Medical prognosis Middle Aged Patients Prognosis Recurrence Remission (Medicine) Resource-Limited Settings Skin Neoplasms - pathology Stem cell transplantation Tumors |
| title | Diagnosing and Treating Blastic Plasmacytoid Dendritic Cell Neoplasm in a Resource-Limited Setting |
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