Lower cerebrovascular reactivity in prefrontal cortex and weaker negative functional connectivity between prefrontal cortex and insula contribute to white matter hyperintensity-related anxiety or depression

White matter hyperintensities (WMHs) are associated with higher anxiety or depression (A/D) incidence. We investigated associations of WMHs with A/D, cerebrovascular reactivity (CVR), and functional connectivity (FC) to identify potential pathomechanisms. Participants with WMH (n = 239) and normal c...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of affective disorders 2024-06, Vol.354, p.526-535
Hauptverfasser:	Huang, Lili, Liu, Xin, Cheng, Yue, Qin, Ruomeng, Yang, Dan, Mo, Yuting, Ke, Zhihong, Hu, Zheqi, Mao, Chenglu, Chen, Ying, Li, Jingwei, Xu, Yun
Format:	Artikel
Sprache:	eng
Schlagworte:	Anxiety Cerebrovascular reactivity Depression Functional connectivity White matter hyperintensity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!