Platelets Affect the Activity of Amino Acid Transporter SNAT4 in HuH-7 Human Hepatoma Cells

Platelets have been reported to exert diverse actions besides hemostasis and thrombus formation in the body. However, whether platelets affect transporter activity remains to be determined. In this study, we examined the effects of platelets on the activity of amino acid transporter system A, which...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2024/03/19, Vol.47(3), pp.652-659
Hauptverfasser:	Kashiwagi, Hitoshi, Sato, Yuki, Nashimoto, Shunsuke, Imai, Shungo, Takekuma, Yoh, Sugawara, Mitsuru
Format:	Artikel
Sprache:	eng
Schlagworte:	activated platelet supernatant Amino Acid Transport Systems - metabolism Amino acids Blood Platelets - metabolism Carcinoma, Hepatocellular Cell Membrane - metabolism Down-regulation Gene expression Hemostasis Hepatoma Humans Liver cancer Liver Neoplasms mRNA platelet Platelets RNA, Messenger - genetics sodium-coupled neutral amino acid transporter 4 system A Thrombosis transport activity
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