Establishing the sensitivity and specificity of the gynaecological cancer distress screen
Objective Nuanced distress screening tools can help cancer care services manage specific cancer groups' concerns more efficiently. This study examines the sensitivity and specificity of a tool specifically for women with gynaecological cancers (called the Gynaecological Cancer Distress Screen o...
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creator | Seib, Charrlotte Harbeck, Emma Anderson, Debra Porter‐Steele, Janine Nehill, Caroline Sanmugarajah, Jasotha Perrin, Lewis Shannon, Catherine Cabraal, Nimithri Jennings, Bronwyn Otton, Geoffrey Adams, Catherine Mellon, Anne Chambers, Suzanne |
description | Objective
Nuanced distress screening tools can help cancer care services manage specific cancer groups' concerns more efficiently. This study examines the sensitivity and specificity of a tool specifically for women with gynaecological cancers (called the Gynaecological Cancer Distress Screen or DT‐Gyn).
Methods
This paper presents cross‐sectional data from individuals recently treated for gynaecological cancer recruited through Australian cancer care services, partner organisations, and support/advocacy services. Receiver operating characteristics analyses were used to evaluate the diagnostic accuracy of the DT‐Gyn against criterion measures for anxiety (GAD‐7), depression (patient health questionnaire), and distress (IES‐R and K10).
Results
Overall, 373 individuals aged 19–91 provided complete data for the study. Using the recognised distress thermometer (DT) cut‐off of 4, 47% of participants were classified as distressed, while a cut‐off of 5 suggested that 40% had clinically relevant distress. The DT‐Gyn showed good discriminant ability across all measures (IES‐R: area under the curve (AUC) = 0.86, 95% CI = 0.82–0.90; GAD‐7: AUC = 0.89, 95% CI = 0.85–0.93; K10: AUC = 0.88, 95% CI = 0.85–0.92; PHQ‐9: AUC = 0.85, 95% CI = 0.81–0.89) and the Youden Index suggested an optimum DT cut‐point of 5.
Conclusions
This study established the psychometric properties of the DT‐Gyn, a tool designed to identify and manage the common sources of distress in women with gynaecological cancers. We suggest a DT cut point ≥5 is optimal in detecting ‘clinically relevant’ distress, anxiety, and depression in this population. |
doi_str_mv | 10.1002/pon.6328 |
format | Article |
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Nuanced distress screening tools can help cancer care services manage specific cancer groups' concerns more efficiently. This study examines the sensitivity and specificity of a tool specifically for women with gynaecological cancers (called the Gynaecological Cancer Distress Screen or DT‐Gyn).
Methods
This paper presents cross‐sectional data from individuals recently treated for gynaecological cancer recruited through Australian cancer care services, partner organisations, and support/advocacy services. Receiver operating characteristics analyses were used to evaluate the diagnostic accuracy of the DT‐Gyn against criterion measures for anxiety (GAD‐7), depression (patient health questionnaire), and distress (IES‐R and K10).
Results
Overall, 373 individuals aged 19–91 provided complete data for the study. Using the recognised distress thermometer (DT) cut‐off of 4, 47% of participants were classified as distressed, while a cut‐off of 5 suggested that 40% had clinically relevant distress. The DT‐Gyn showed good discriminant ability across all measures (IES‐R: area under the curve (AUC) = 0.86, 95% CI = 0.82–0.90; GAD‐7: AUC = 0.89, 95% CI = 0.85–0.93; K10: AUC = 0.88, 95% CI = 0.85–0.92; PHQ‐9: AUC = 0.85, 95% CI = 0.81–0.89) and the Youden Index suggested an optimum DT cut‐point of 5.
Conclusions
This study established the psychometric properties of the DT‐Gyn, a tool designed to identify and manage the common sources of distress in women with gynaecological cancers. We suggest a DT cut point ≥5 is optimal in detecting ‘clinically relevant’ distress, anxiety, and depression in this population.</description><identifier>ISSN: 1057-9249</identifier><identifier>EISSN: 1099-1611</identifier><identifier>DOI: 10.1002/pon.6328</identifier><identifier>PMID: 38504431</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Advocacy ; Anxiety ; Anxiety - diagnosis ; Anxiety - epidemiology ; Australia ; Cancer ; Cross-Sectional Studies ; Depression - diagnosis ; Depression - epidemiology ; distress thermometer ; Female ; Generalized anxiety disorder ; Genital Neoplasms, Female - diagnosis ; gynaecological cancer ; Gynecological cancer ; Gynecology ; Humans ; Mass Screening ; Medical screening ; Mental depression ; Neoplasms - epidemiology ; oncology ; Psychological distress ; psychological support ; Psychometrics ; psycho‐oncology ; Quantitative psychology ; routine screening ; sensitivity ; Sensitivity and Specificity ; specificity ; Stress, Psychological - diagnosis ; Stress, Psychological - epidemiology ; Surveys and Questionnaires ; Women</subject><ispartof>Psycho-oncology (Chichester, England), 2024-03, Vol.33 (3), p.e6328-n/a</ispartof><rights>2024 The Authors. Psycho‐Oncology published by John Wiley & Sons Ltd.</rights><rights>2024 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.</rights><rights>2024. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3448-9953bad90e4825cc9440cae50c006a12fb79069c126559798cbae41604a55e7b3</cites><orcidid>0000-0003-2369-6111 ; 0000-0002-7055-9438</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpon.6328$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpon.6328$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,30999,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38504431$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Seib, Charrlotte</creatorcontrib><creatorcontrib>Harbeck, Emma</creatorcontrib><creatorcontrib>Anderson, Debra</creatorcontrib><creatorcontrib>Porter‐Steele, Janine</creatorcontrib><creatorcontrib>Nehill, Caroline</creatorcontrib><creatorcontrib>Sanmugarajah, Jasotha</creatorcontrib><creatorcontrib>Perrin, Lewis</creatorcontrib><creatorcontrib>Shannon, Catherine</creatorcontrib><creatorcontrib>Cabraal, Nimithri</creatorcontrib><creatorcontrib>Jennings, Bronwyn</creatorcontrib><creatorcontrib>Otton, Geoffrey</creatorcontrib><creatorcontrib>Adams, Catherine</creatorcontrib><creatorcontrib>Mellon, Anne</creatorcontrib><creatorcontrib>Chambers, Suzanne</creatorcontrib><title>Establishing the sensitivity and specificity of the gynaecological cancer distress screen</title><title>Psycho-oncology (Chichester, England)</title><addtitle>Psychooncology</addtitle><description>Objective
Nuanced distress screening tools can help cancer care services manage specific cancer groups' concerns more efficiently. This study examines the sensitivity and specificity of a tool specifically for women with gynaecological cancers (called the Gynaecological Cancer Distress Screen or DT‐Gyn).
Methods
This paper presents cross‐sectional data from individuals recently treated for gynaecological cancer recruited through Australian cancer care services, partner organisations, and support/advocacy services. Receiver operating characteristics analyses were used to evaluate the diagnostic accuracy of the DT‐Gyn against criterion measures for anxiety (GAD‐7), depression (patient health questionnaire), and distress (IES‐R and K10).
Results
Overall, 373 individuals aged 19–91 provided complete data for the study. Using the recognised distress thermometer (DT) cut‐off of 4, 47% of participants were classified as distressed, while a cut‐off of 5 suggested that 40% had clinically relevant distress. The DT‐Gyn showed good discriminant ability across all measures (IES‐R: area under the curve (AUC) = 0.86, 95% CI = 0.82–0.90; GAD‐7: AUC = 0.89, 95% CI = 0.85–0.93; K10: AUC = 0.88, 95% CI = 0.85–0.92; PHQ‐9: AUC = 0.85, 95% CI = 0.81–0.89) and the Youden Index suggested an optimum DT cut‐point of 5.
Conclusions
This study established the psychometric properties of the DT‐Gyn, a tool designed to identify and manage the common sources of distress in women with gynaecological cancers. We suggest a DT cut point ≥5 is optimal in detecting ‘clinically relevant’ distress, anxiety, and depression in this population.</description><subject>Advocacy</subject><subject>Anxiety</subject><subject>Anxiety - diagnosis</subject><subject>Anxiety - epidemiology</subject><subject>Australia</subject><subject>Cancer</subject><subject>Cross-Sectional Studies</subject><subject>Depression - diagnosis</subject><subject>Depression - epidemiology</subject><subject>distress thermometer</subject><subject>Female</subject><subject>Generalized anxiety disorder</subject><subject>Genital Neoplasms, Female - diagnosis</subject><subject>gynaecological cancer</subject><subject>Gynecological cancer</subject><subject>Gynecology</subject><subject>Humans</subject><subject>Mass Screening</subject><subject>Medical screening</subject><subject>Mental depression</subject><subject>Neoplasms - epidemiology</subject><subject>oncology</subject><subject>Psychological distress</subject><subject>psychological support</subject><subject>Psychometrics</subject><subject>psycho‐oncology</subject><subject>Quantitative psychology</subject><subject>routine screening</subject><subject>sensitivity</subject><subject>Sensitivity and Specificity</subject><subject>specificity</subject><subject>Stress, Psychological - diagnosis</subject><subject>Stress, Psychological - epidemiology</subject><subject>Surveys and Questionnaires</subject><subject>Women</subject><issn>1057-9249</issn><issn>1099-1611</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNp10EtLxDAUhuEgijNewF8gBTduOp60SdosRbyBqAtduCppejpGOmnN6Sj993YcLyC4SgIPL-Fj7IDDjAMkJ13rZypN8g025aB1zBXnm6u7zGKdCD1hO0QvACPWaptN0lyCECmfsqdz6k3ZOHp2fh71zxgRenK9e3P9EBlfRdShdbWzq3dbf5L54A3atmnnzpomssZbDFHlqA9IFJENiH6PbdWmIdz_OnfZ48X5w9lVfHN3eX12ehPbVIg81lqmpak0oMgTaa0WAqxBCRZAGZ7UZaZBacsTJaXOdG5Lg4IrEEZKzMp0lx2vu11oX5dIfbFwZLFpjMd2SUWisyQDCSBGevSHvrTL4MffjSpXIlc5V79BG1qigHXRBbcwYSg4FKu5i3HuYjX3SA-_gstygdUP_N53BPEavLsGh39Dxf3d7WfwAwMQiKs</recordid><startdate>202403</startdate><enddate>202403</enddate><creator>Seib, Charrlotte</creator><creator>Harbeck, Emma</creator><creator>Anderson, Debra</creator><creator>Porter‐Steele, Janine</creator><creator>Nehill, Caroline</creator><creator>Sanmugarajah, Jasotha</creator><creator>Perrin, Lewis</creator><creator>Shannon, Catherine</creator><creator>Cabraal, Nimithri</creator><creator>Jennings, Bronwyn</creator><creator>Otton, Geoffrey</creator><creator>Adams, Catherine</creator><creator>Mellon, Anne</creator><creator>Chambers, Suzanne</creator><general>Wiley Subscription Services, Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QJ</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2369-6111</orcidid><orcidid>https://orcid.org/0000-0002-7055-9438</orcidid></search><sort><creationdate>202403</creationdate><title>Establishing the sensitivity and specificity of the gynaecological cancer distress screen</title><author>Seib, Charrlotte ; Harbeck, Emma ; Anderson, Debra ; Porter‐Steele, Janine ; Nehill, Caroline ; Sanmugarajah, Jasotha ; Perrin, Lewis ; Shannon, Catherine ; Cabraal, Nimithri ; Jennings, Bronwyn ; Otton, Geoffrey ; Adams, Catherine ; Mellon, Anne ; Chambers, Suzanne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3448-9953bad90e4825cc9440cae50c006a12fb79069c126559798cbae41604a55e7b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Advocacy</topic><topic>Anxiety</topic><topic>Anxiety - diagnosis</topic><topic>Anxiety - epidemiology</topic><topic>Australia</topic><topic>Cancer</topic><topic>Cross-Sectional Studies</topic><topic>Depression - diagnosis</topic><topic>Depression - epidemiology</topic><topic>distress thermometer</topic><topic>Female</topic><topic>Generalized anxiety disorder</topic><topic>Genital Neoplasms, Female - diagnosis</topic><topic>gynaecological cancer</topic><topic>Gynecological cancer</topic><topic>Gynecology</topic><topic>Humans</topic><topic>Mass Screening</topic><topic>Medical screening</topic><topic>Mental depression</topic><topic>Neoplasms - epidemiology</topic><topic>oncology</topic><topic>Psychological distress</topic><topic>psychological support</topic><topic>Psychometrics</topic><topic>psycho‐oncology</topic><topic>Quantitative psychology</topic><topic>routine screening</topic><topic>sensitivity</topic><topic>Sensitivity and Specificity</topic><topic>specificity</topic><topic>Stress, Psychological - diagnosis</topic><topic>Stress, Psychological - epidemiology</topic><topic>Surveys and Questionnaires</topic><topic>Women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Seib, Charrlotte</creatorcontrib><creatorcontrib>Harbeck, Emma</creatorcontrib><creatorcontrib>Anderson, Debra</creatorcontrib><creatorcontrib>Porter‐Steele, Janine</creatorcontrib><creatorcontrib>Nehill, Caroline</creatorcontrib><creatorcontrib>Sanmugarajah, Jasotha</creatorcontrib><creatorcontrib>Perrin, Lewis</creatorcontrib><creatorcontrib>Shannon, Catherine</creatorcontrib><creatorcontrib>Cabraal, Nimithri</creatorcontrib><creatorcontrib>Jennings, Bronwyn</creatorcontrib><creatorcontrib>Otton, Geoffrey</creatorcontrib><creatorcontrib>Adams, Catherine</creatorcontrib><creatorcontrib>Mellon, Anne</creatorcontrib><creatorcontrib>Chambers, Suzanne</creatorcontrib><collection>Wiley Online Library (Open Access Collection)</collection><collection>Wiley Online Library (Open Access Collection)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Psycho-oncology (Chichester, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Seib, Charrlotte</au><au>Harbeck, Emma</au><au>Anderson, Debra</au><au>Porter‐Steele, Janine</au><au>Nehill, Caroline</au><au>Sanmugarajah, Jasotha</au><au>Perrin, Lewis</au><au>Shannon, Catherine</au><au>Cabraal, Nimithri</au><au>Jennings, Bronwyn</au><au>Otton, Geoffrey</au><au>Adams, Catherine</au><au>Mellon, Anne</au><au>Chambers, Suzanne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Establishing the sensitivity and specificity of the gynaecological cancer distress screen</atitle><jtitle>Psycho-oncology (Chichester, England)</jtitle><addtitle>Psychooncology</addtitle><date>2024-03</date><risdate>2024</risdate><volume>33</volume><issue>3</issue><spage>e6328</spage><epage>n/a</epage><pages>e6328-n/a</pages><issn>1057-9249</issn><eissn>1099-1611</eissn><abstract>Objective
Nuanced distress screening tools can help cancer care services manage specific cancer groups' concerns more efficiently. This study examines the sensitivity and specificity of a tool specifically for women with gynaecological cancers (called the Gynaecological Cancer Distress Screen or DT‐Gyn).
Methods
This paper presents cross‐sectional data from individuals recently treated for gynaecological cancer recruited through Australian cancer care services, partner organisations, and support/advocacy services. Receiver operating characteristics analyses were used to evaluate the diagnostic accuracy of the DT‐Gyn against criterion measures for anxiety (GAD‐7), depression (patient health questionnaire), and distress (IES‐R and K10).
Results
Overall, 373 individuals aged 19–91 provided complete data for the study. Using the recognised distress thermometer (DT) cut‐off of 4, 47% of participants were classified as distressed, while a cut‐off of 5 suggested that 40% had clinically relevant distress. The DT‐Gyn showed good discriminant ability across all measures (IES‐R: area under the curve (AUC) = 0.86, 95% CI = 0.82–0.90; GAD‐7: AUC = 0.89, 95% CI = 0.85–0.93; K10: AUC = 0.88, 95% CI = 0.85–0.92; PHQ‐9: AUC = 0.85, 95% CI = 0.81–0.89) and the Youden Index suggested an optimum DT cut‐point of 5.
Conclusions
This study established the psychometric properties of the DT‐Gyn, a tool designed to identify and manage the common sources of distress in women with gynaecological cancers. We suggest a DT cut point ≥5 is optimal in detecting ‘clinically relevant’ distress, anxiety, and depression in this population.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>38504431</pmid><doi>10.1002/pon.6328</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0003-2369-6111</orcidid><orcidid>https://orcid.org/0000-0002-7055-9438</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Advocacy Anxiety Anxiety - diagnosis Anxiety - epidemiology Australia Cancer Cross-Sectional Studies Depression - diagnosis Depression - epidemiology distress thermometer Female Generalized anxiety disorder Genital Neoplasms, Female - diagnosis gynaecological cancer Gynecological cancer Gynecology Humans Mass Screening Medical screening Mental depression Neoplasms - epidemiology oncology Psychological distress psychological support Psychometrics psycho‐oncology Quantitative psychology routine screening sensitivity Sensitivity and Specificity specificity Stress, Psychological - diagnosis Stress, Psychological - epidemiology Surveys and Questionnaires Women |
title | Establishing the sensitivity and specificity of the gynaecological cancer distress screen |
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