Effect of NO sub(x) on the Somatic Chromosomes of Goldsmiths

Effect of NO sub(x) on the Somatic Chromosomes of Goldsmiths

In India, 45 goldsmiths exposed to nitrogen oxides and 45 matched controls were screened for genetic damage. The average exposure concentrations for exposed and control subjects were 1770.05 and 50 mu g/m super(3), respectively. Lymphocytes were examined for mitotic index, chromosomal aberrations, a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Environmental health perspectives 1998-10, Vol.106 (10), p.643-647
Hauptverfasser: Yadav, J S, Seth, N
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 647
container_issue 10
container_start_page 643
container_title Environmental health perspectives
container_volume 106
creator Yadav, J S
Seth, N
description In India, 45 goldsmiths exposed to nitrogen oxides and 45 matched controls were screened for genetic damage. The average exposure concentrations for exposed and control subjects were 1770.05 and 50 mu g/m super(3), respectively. Lymphocytes were examined for mitotic index, chromosomal aberrations, and satellite associations. Results showed that 30 out of the 45 occupationally exposed subjects complained of eye irritation, and six were asthmatics. There was a significant increase in total chromosomal aberrations in the exposed group compared to the controls. In addition, a high frequency of dicentrics was found, and the frequency of sister chromatid exchanges in goldsmiths was higher than in controls. A twofold increase in the frequency of satellite associations per cell was observed, and after 5 yr of employment, the mitotic index showed a gradual decline.
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_29707565</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>17130930</sourcerecordid><originalsourceid>FETCH-LOGICAL-p935-9237c2aec6696f4021b6040f30079f022159072b15cd2fc791405255324075bd3</originalsourceid><addsrcrecordid>eNqFzM1KAzEUQOEsFFqr75CV6GLg5ubPgBsZai0Uu7D7MpNJmCmTpvZmwMdX0X1XZ_NxrtgcwInKWKNn7IboAADiyZg5e17GGHzhOfL3Laepffh65PnISx_4R05NGTyv-3NOmXIK9OtWeewoDaWnW3Ydm5HC3X8XbPe63NVv1Wa7Wtcvm-rkpK4cSuuxCd4YZ6ICFK0BBVECWBcBUWgHFluhfYfRWycUaNRaogKr204u2P3f9nTOn1Ogsk8D-TCOzTHkifbo7A80-iIUVkhwEi5DpUGCBfkNOY5btQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>14503070</pqid></control><display><type>article</type><title>Effect of NO sub(x) on the Somatic Chromosomes of Goldsmiths</title><source>DOAJ Directory of Open Access Journals</source><source>PubMed Central Open Access</source><source>JSTOR Archive Collection A-Z Listing</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Yadav, J S ; Seth, N</creator><creatorcontrib>Yadav, J S ; Seth, N</creatorcontrib><description>In India, 45 goldsmiths exposed to nitrogen oxides and 45 matched controls were screened for genetic damage. The average exposure concentrations for exposed and control subjects were 1770.05 and 50 mu g/m super(3), respectively. Lymphocytes were examined for mitotic index, chromosomal aberrations, and satellite associations. Results showed that 30 out of the 45 occupationally exposed subjects complained of eye irritation, and six were asthmatics. There was a significant increase in total chromosomal aberrations in the exposed group compared to the controls. In addition, a high frequency of dicentrics was found, and the frequency of sister chromatid exchanges in goldsmiths was higher than in controls. A twofold increase in the frequency of satellite associations per cell was observed, and after 5 yr of employment, the mitotic index showed a gradual decline.</description><identifier>ISSN: 0091-6765</identifier><language>eng</language><ispartof>Environmental health perspectives, 1998-10, Vol.106 (10), p.643-647</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids></links><search><creatorcontrib>Yadav, J S</creatorcontrib><creatorcontrib>Seth, N</creatorcontrib><title>Effect of NO sub(x) on the Somatic Chromosomes of Goldsmiths</title><title>Environmental health perspectives</title><description>In India, 45 goldsmiths exposed to nitrogen oxides and 45 matched controls were screened for genetic damage. The average exposure concentrations for exposed and control subjects were 1770.05 and 50 mu g/m super(3), respectively. Lymphocytes were examined for mitotic index, chromosomal aberrations, and satellite associations. Results showed that 30 out of the 45 occupationally exposed subjects complained of eye irritation, and six were asthmatics. There was a significant increase in total chromosomal aberrations in the exposed group compared to the controls. In addition, a high frequency of dicentrics was found, and the frequency of sister chromatid exchanges in goldsmiths was higher than in controls. A twofold increase in the frequency of satellite associations per cell was observed, and after 5 yr of employment, the mitotic index showed a gradual decline.</description><issn>0091-6765</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><recordid>eNqFzM1KAzEUQOEsFFqr75CV6GLg5ubPgBsZai0Uu7D7MpNJmCmTpvZmwMdX0X1XZ_NxrtgcwInKWKNn7IboAADiyZg5e17GGHzhOfL3Laepffh65PnISx_4R05NGTyv-3NOmXIK9OtWeewoDaWnW3Ydm5HC3X8XbPe63NVv1Wa7Wtcvm-rkpK4cSuuxCd4YZ6ICFK0BBVECWBcBUWgHFluhfYfRWycUaNRaogKr204u2P3f9nTOn1Ogsk8D-TCOzTHkifbo7A80-iIUVkhwEi5DpUGCBfkNOY5btQ</recordid><startdate>19981001</startdate><enddate>19981001</enddate><creator>Yadav, J S</creator><creator>Seth, N</creator><scope>7ST</scope><scope>C1K</scope><scope>SOI</scope><scope>7T2</scope><scope>7U2</scope><scope>7U7</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>19981001</creationdate><title>Effect of NO sub(x) on the Somatic Chromosomes of Goldsmiths</title><author>Yadav, J S ; Seth, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p935-9237c2aec6696f4021b6040f30079f022159072b15cd2fc791405255324075bd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yadav, J S</creatorcontrib><creatorcontrib>Seth, N</creatorcontrib><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Safety Science and Risk</collection><collection>Toxicology Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Environmental health perspectives</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yadav, J S</au><au>Seth, N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of NO sub(x) on the Somatic Chromosomes of Goldsmiths</atitle><jtitle>Environmental health perspectives</jtitle><date>1998-10-01</date><risdate>1998</risdate><volume>106</volume><issue>10</issue><spage>643</spage><epage>647</epage><pages>643-647</pages><issn>0091-6765</issn><abstract>In India, 45 goldsmiths exposed to nitrogen oxides and 45 matched controls were screened for genetic damage. The average exposure concentrations for exposed and control subjects were 1770.05 and 50 mu g/m super(3), respectively. Lymphocytes were examined for mitotic index, chromosomal aberrations, and satellite associations. Results showed that 30 out of the 45 occupationally exposed subjects complained of eye irritation, and six were asthmatics. There was a significant increase in total chromosomal aberrations in the exposed group compared to the controls. In addition, a high frequency of dicentrics was found, and the frequency of sister chromatid exchanges in goldsmiths was higher than in controls. A twofold increase in the frequency of satellite associations per cell was observed, and after 5 yr of employment, the mitotic index showed a gradual decline.</abstract><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0091-6765
ispartof Environmental health perspectives, 1998-10, Vol.106 (10), p.643-647
issn 0091-6765
language eng
recordid cdi_proquest_miscellaneous_29707565
source DOAJ Directory of Open Access Journals; PubMed Central Open Access; JSTOR Archive Collection A-Z Listing; EZB-FREE-00999 freely available EZB journals; PubMed Central
title Effect of NO sub(x) on the Somatic Chromosomes of Goldsmiths
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T12%3A43%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20NO%20sub(x)%20on%20the%20Somatic%20Chromosomes%20of%20Goldsmiths&rft.jtitle=Environmental%20health%20perspectives&rft.au=Yadav,%20J%20S&rft.date=1998-10-01&rft.volume=106&rft.issue=10&rft.spage=643&rft.epage=647&rft.pages=643-647&rft.issn=0091-6765&rft_id=info:doi/&rft_dat=%3Cproquest%3E17130930%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=14503070&rft_id=info:pmid/&rfr_iscdi=true