Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry
Cardioneuroablation has been emerging as a potential treatment alternative in appropriately selected patients with cardioinhibitory vasovagal syncope (VVS) and functional AV block (AVB). However the majority of available evidence has been derived from retrospective cohort studies performed by experi...
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| Veröffentlicht in: | Journal of interventional cardiac electrophysiology 2024-03 |
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| creator | Aksu, Tolga Tung, Roderick De Potter, Tom Markman, Timothy M Santangeli, Pasquale du Fay de Lavallaz, Jeanne Winterfield, Jeffrey R Baykaner, Tina Alyesh, Daniel Joza, Jacqueline E Gopinathannair, Rakesh Badertscher, Patrick Do, Duc H Hussein, Ayman Osorio, Jose Dewland, Thomas Perino, Alexander Rodgers, Albert J DeSimone, Christopher Alfie, Alberto Atwater, Brett D Singh, David Kumar, Kapil Salcedo, Jonathan Bradfield, Jason S Upadhyay, Gaurav Sood, Nitesh Sharma, Parikshit S Gautam, Sandeep Kumar, Vineet Forno, Alexander Romeno Janner Dal Woods, Christopher E Rav-Acha, Moshe Valeriano, Chiara Kapur, Sunil Enriquez, Andres Sundaram, Sri Glikson, Michael Gerstenfeld, Edward Piccini, Jonathan Tzou, Wendy S Sauer, William d'Avila, Andre Shivkumar, Kalyanam Huang, Henry D |
| description | Cardioneuroablation has been emerging as a potential treatment alternative in appropriately selected patients with cardioinhibitory vasovagal syncope (VVS) and functional AV block (AVB). However the majority of available evidence has been derived from retrospective cohort studies performed by experienced operators.
The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patients treated by conservative therapy and CNA.
The study is a prospective observational registry with cross-over design for analysis of outcomes between a control group (i.e., behavioral and medical therapy only) and intervention group (Cardioneuroablation). Primary and secondary outcomes will only be assessed after enrollment in the registry. The follow-up period will be 3 years after enrollment.
There remains a lack of prospective multicentered data for long-term outcomes comparing conservative therapy to radiofrequency CNA procedures particularly for key outcomes including recurrence of syncope, AV block, durable impact of disruption of the autonomic nervous system, and long-term complications after CNA. The CNA-FWRD registry has the potential to help fill this information gap. |
| doi_str_mv | 10.1007/s10840-024-01789-9 |
| format | Article |
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The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patients treated by conservative therapy and CNA.
The study is a prospective observational registry with cross-over design for analysis of outcomes between a control group (i.e., behavioral and medical therapy only) and intervention group (Cardioneuroablation). Primary and secondary outcomes will only be assessed after enrollment in the registry. The follow-up period will be 3 years after enrollment.
There remains a lack of prospective multicentered data for long-term outcomes comparing conservative therapy to radiofrequency CNA procedures particularly for key outcomes including recurrence of syncope, AV block, durable impact of disruption of the autonomic nervous system, and long-term complications after CNA. The CNA-FWRD registry has the potential to help fill this information gap.</description><identifier>ISSN: 1572-8595</identifier><identifier>EISSN: 1572-8595</identifier><identifier>DOI: 10.1007/s10840-024-01789-9</identifier><identifier>PMID: 38499825</identifier><language>eng</language><publisher>Netherlands</publisher><ispartof>Journal of interventional cardiac electrophysiology, 2024-03</ispartof><rights>2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c254t-fe80b88daaa3534c1fdca9cff040cea653e7f36fd69437009dc001e2124f87bb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38499825$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aksu, Tolga</creatorcontrib><creatorcontrib>Tung, Roderick</creatorcontrib><creatorcontrib>De Potter, Tom</creatorcontrib><creatorcontrib>Markman, Timothy M</creatorcontrib><creatorcontrib>Santangeli, Pasquale</creatorcontrib><creatorcontrib>du Fay de Lavallaz, Jeanne</creatorcontrib><creatorcontrib>Winterfield, Jeffrey R</creatorcontrib><creatorcontrib>Baykaner, Tina</creatorcontrib><creatorcontrib>Alyesh, Daniel</creatorcontrib><creatorcontrib>Joza, Jacqueline E</creatorcontrib><creatorcontrib>Gopinathannair, Rakesh</creatorcontrib><creatorcontrib>Badertscher, Patrick</creatorcontrib><creatorcontrib>Do, Duc H</creatorcontrib><creatorcontrib>Hussein, Ayman</creatorcontrib><creatorcontrib>Osorio, Jose</creatorcontrib><creatorcontrib>Dewland, Thomas</creatorcontrib><creatorcontrib>Perino, Alexander</creatorcontrib><creatorcontrib>Rodgers, Albert J</creatorcontrib><creatorcontrib>DeSimone, Christopher</creatorcontrib><creatorcontrib>Alfie, Alberto</creatorcontrib><creatorcontrib>Atwater, Brett D</creatorcontrib><creatorcontrib>Singh, David</creatorcontrib><creatorcontrib>Kumar, Kapil</creatorcontrib><creatorcontrib>Salcedo, Jonathan</creatorcontrib><creatorcontrib>Bradfield, Jason S</creatorcontrib><creatorcontrib>Upadhyay, Gaurav</creatorcontrib><creatorcontrib>Sood, Nitesh</creatorcontrib><creatorcontrib>Sharma, Parikshit S</creatorcontrib><creatorcontrib>Gautam, Sandeep</creatorcontrib><creatorcontrib>Kumar, Vineet</creatorcontrib><creatorcontrib>Forno, Alexander Romeno Janner Dal</creatorcontrib><creatorcontrib>Woods, Christopher E</creatorcontrib><creatorcontrib>Rav-Acha, Moshe</creatorcontrib><creatorcontrib>Valeriano, Chiara</creatorcontrib><creatorcontrib>Kapur, Sunil</creatorcontrib><creatorcontrib>Enriquez, Andres</creatorcontrib><creatorcontrib>Sundaram, Sri</creatorcontrib><creatorcontrib>Glikson, Michael</creatorcontrib><creatorcontrib>Gerstenfeld, Edward</creatorcontrib><creatorcontrib>Piccini, Jonathan</creatorcontrib><creatorcontrib>Tzou, Wendy S</creatorcontrib><creatorcontrib>Sauer, William</creatorcontrib><creatorcontrib>d'Avila, Andre</creatorcontrib><creatorcontrib>Shivkumar, Kalyanam</creatorcontrib><creatorcontrib>Huang, Henry D</creatorcontrib><title>Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry</title><title>Journal of interventional cardiac electrophysiology</title><addtitle>J Interv Card Electrophysiol</addtitle><description>Cardioneuroablation has been emerging as a potential treatment alternative in appropriately selected patients with cardioinhibitory vasovagal syncope (VVS) and functional AV block (AVB). However the majority of available evidence has been derived from retrospective cohort studies performed by experienced operators.
The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patients treated by conservative therapy and CNA.
The study is a prospective observational registry with cross-over design for analysis of outcomes between a control group (i.e., behavioral and medical therapy only) and intervention group (Cardioneuroablation). Primary and secondary outcomes will only be assessed after enrollment in the registry. The follow-up period will be 3 years after enrollment.
There remains a lack of prospective multicentered data for long-term outcomes comparing conservative therapy to radiofrequency CNA procedures particularly for key outcomes including recurrence of syncope, AV block, durable impact of disruption of the autonomic nervous system, and long-term complications after CNA. 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Electrophysiol</addtitle><date>2024-03-18</date><risdate>2024</risdate><issn>1572-8595</issn><eissn>1572-8595</eissn><abstract>Cardioneuroablation has been emerging as a potential treatment alternative in appropriately selected patients with cardioinhibitory vasovagal syncope (VVS) and functional AV block (AVB). However the majority of available evidence has been derived from retrospective cohort studies performed by experienced operators.
The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patients treated by conservative therapy and CNA.
The study is a prospective observational registry with cross-over design for analysis of outcomes between a control group (i.e., behavioral and medical therapy only) and intervention group (Cardioneuroablation). Primary and secondary outcomes will only be assessed after enrollment in the registry. The follow-up period will be 3 years after enrollment.
There remains a lack of prospective multicentered data for long-term outcomes comparing conservative therapy to radiofrequency CNA procedures particularly for key outcomes including recurrence of syncope, AV block, durable impact of disruption of the autonomic nervous system, and long-term complications after CNA. The CNA-FWRD registry has the potential to help fill this information gap.</abstract><cop>Netherlands</cop><pmid>38499825</pmid><doi>10.1007/s10840-024-01789-9</doi></addata></record> |
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| title | Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry |
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