A Comprehensive Examination of Heterocyclic Scaffold Chemistry for Antitubercular Activity
Tuberculosis is a communicable disease which affects humans particularly the lungs and is transmitted mainly through air. Despite two decades of intensive research aimed at understanding and combating tuberculosis, persistent biological uncertainties continue to hinder progress. Nowadays, heterocycl...
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| Veröffentlicht in: | Chemistry & biodiversity 2024-05, Vol.21 (5), p.e202400067-n/a |
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| creator | Bendi, Anjaneyulu Yadav, Priyanka Saini, Komal Singh Bhathiwal, Anirudh Raghav, Neera |
| description | Tuberculosis is a communicable disease which affects humans particularly the lungs and is transmitted mainly through air. Despite two decades of intensive research aimed at understanding and combating tuberculosis, persistent biological uncertainties continue to hinder progress. Nowadays, heterocyclic compounds have proven themselves in effective treatment of tuberculosis because of their wide range of biological and pharmacological activities. Antituberculosis or antimycobacterial agents encompass a broad array of compounds utilized singly or in conjunction to combat Mycobacterium infections, spanning from tuberculosis to leprosy. Here, we summarize the synthesis of various heterocyclic compounds which includes the greener synthetic route as well as use of nano compounds as catalyst along with their anti TB activities. |
| doi_str_mv | 10.1002/cbdv.202400067 |
| format | Article |
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| subjects | Academics Antimycobacterial agents Antitubercular Activities Antitubercular Agents - chemical synthesis Antitubercular Agents - chemistry Antitubercular Agents - pharmacology Catalysts Chemical activity Heterocycle Scaffolds Heterocyclic compounds Heterocyclic Compounds - chemical synthesis Heterocyclic Compounds - chemistry Heterocyclic Compounds - pharmacology Humans Microbial Sensitivity Tests Molecular Structure Mycobacterium tuberculosis - drug effects Pharmaceutical Sector and Tuberculosis Research Tuberculosis Tuberculosis - drug therapy |
| title | A Comprehensive Examination of Heterocyclic Scaffold Chemistry for Antitubercular Activity |
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