IL-10 Differentially Promotes Mast Cell Responsiveness to IL-33, Resulting in Enhancement of Type 2 Inflammation and Suppression of Neutrophilia

Mast cells (MCs) play critical roles in the establishment of allergic diseases. We recently demonstrated an unexpected, proinflammatory role for IL-10 in regulating MC responses. IL-10 enhanced MC activation and promoted IgE-dependent responses during food allergy. However, whether these effects ext...

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Veröffentlicht in:	The Journal of immunology (1950) 2024-05, Vol.212 (9), p.1407-1419
Hauptverfasser:	Ranjitkar, Saurav, Krajewski, Dylan, Garcia, Chelsea, Tedeschi, Caitlin, Polukort, Stephanie H, Rovatti, Jeffrey, Mire, Mohamed, Blesso, Christopher N, Jellison, Evan, Schneider, Sallie S, Ryan, John J, Mathias, Clinton B
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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