Construction Occupations, Asbestos Exposure, and Cancer of the Colon and Rectum
Colorectal cancer affects more than 157,000 Americans annually. Occupational risk from exposure to asbestos dust has been implicated, leading us to explore further the possible association between colorectal cancer and asbestos. Two hundred sixty-one cases of colon and rectal cancer and 183 control...
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Veröffentlicht in: | Journal of occupational and environmental medicine 1994-09, Vol.36 (9), p.1027-1031 |
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container_title | Journal of occupational and environmental medicine |
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creator | Demers, Raymond Y. Burns, Patricia Brissette Swanson, G. Marie |
description | Colorectal cancer affects more than 157,000 Americans annually. Occupational risk from exposure to asbestos dust has been implicated, leading us to explore further the possible association between colorectal cancer and asbestos. Two hundred sixty-one cases of colon and rectal cancer and 183 control cases were identified within a large, population-based case-control study conducted in southeast Michigan. Employment in occupations historically known to involve heavy exposure to asbestos was used as a surrogate for asbestos exposure. Cancers of the colon showed reduced odds ratios. Our findings differ substantially from those of the previous studies showing elevated risk. Further study is needed to address the same question, with specified asbestos exposure assessment and control for potentially significant confounders such as physical activity and diet. |
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Further study is needed to address the same question, with specified asbestos exposure assessment and control for potentially significant confounders such as physical activity and diet.</description><identifier>ISSN: 0096-1736</identifier><identifier>ISSN: 1076-2752</identifier><identifier>EISSN: 2332-3795</identifier><identifier>EISSN: 1536-5948</identifier><identifier>PMID: 7823215</identifier><identifier>CODEN: JJOMDZ</identifier><language>eng</language><publisher>Baltimore, MD: Williams & Wilkins</publisher><subject>Adult ; Asbestos ; Asbestos - adverse effects ; Biological and medical sciences ; Cocarcinogenesis ; Colon cancer ; Colorectal Neoplasms - epidemiology ; Colorectal Neoplasms - etiology ; Construction ; Construction Materials - adverse effects ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Male ; Medical sciences ; Mesothelioma - epidemiology ; Mesothelioma - etiology ; Middle Aged ; Occupational Diseases - epidemiology ; Occupational Diseases - etiology ; Occupational Exposure - adverse effects ; Occupations ; Odds Ratio ; ORIGINAL ARTICLES ; Pleural Neoplasms - epidemiology ; Pleural Neoplasms - etiology ; Population Surveillance ; Risk Factors ; Smoking - adverse effects ; Stomach. Duodenum. Small intestine. Colon. Rectum. 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Marie</creatorcontrib><title>Construction Occupations, Asbestos Exposure, and Cancer of the Colon and Rectum</title><title>Journal of occupational and environmental medicine</title><addtitle>J Occup Med</addtitle><description>Colorectal cancer affects more than 157,000 Americans annually. Occupational risk from exposure to asbestos dust has been implicated, leading us to explore further the possible association between colorectal cancer and asbestos. Two hundred sixty-one cases of colon and rectal cancer and 183 control cases were identified within a large, population-based case-control study conducted in southeast Michigan. Employment in occupations historically known to involve heavy exposure to asbestos was used as a surrogate for asbestos exposure. Cancers of the colon showed reduced odds ratios. Our findings differ substantially from those of the previous studies showing elevated risk. Further study is needed to address the same question, with specified asbestos exposure assessment and control for potentially significant confounders such as physical activity and diet.</description><subject>Adult</subject><subject>Asbestos</subject><subject>Asbestos - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Cocarcinogenesis</subject><subject>Colon cancer</subject><subject>Colorectal Neoplasms - epidemiology</subject><subject>Colorectal Neoplasms - etiology</subject><subject>Construction</subject><subject>Construction Materials - adverse effects</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mesothelioma - epidemiology</subject><subject>Mesothelioma - etiology</subject><subject>Middle Aged</subject><subject>Occupational Diseases - epidemiology</subject><subject>Occupational Diseases - etiology</subject><subject>Occupational Exposure - adverse effects</subject><subject>Occupations</subject><subject>Odds Ratio</subject><subject>ORIGINAL ARTICLES</subject><subject>Pleural Neoplasms - epidemiology</subject><subject>Pleural Neoplasms - etiology</subject><subject>Population Surveillance</subject><subject>Risk Factors</subject><subject>Smoking - adverse effects</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Marie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j346t-d3a4723449bb3756961e5efbddc621fab12e9f49d63b64c860fa88239e94cec23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adult</topic><topic>Asbestos</topic><topic>Asbestos - adverse effects</topic><topic>Biological and medical sciences</topic><topic>Cocarcinogenesis</topic><topic>Colon cancer</topic><topic>Colorectal Neoplasms - epidemiology</topic><topic>Colorectal Neoplasms - etiology</topic><topic>Construction</topic><topic>Construction Materials - adverse effects</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. 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Employment in occupations historically known to involve heavy exposure to asbestos was used as a surrogate for asbestos exposure. Cancers of the colon showed reduced odds ratios. Our findings differ substantially from those of the previous studies showing elevated risk. Further study is needed to address the same question, with specified asbestos exposure assessment and control for potentially significant confounders such as physical activity and diet.</abstract><cop>Baltimore, MD</cop><pub>Williams & Wilkins</pub><pmid>7823215</pmid><tpages>5</tpages></addata></record> |
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source | MEDLINE; Journals@Ovid Complete |
subjects | Adult Asbestos Asbestos - adverse effects Biological and medical sciences Cocarcinogenesis Colon cancer Colorectal Neoplasms - epidemiology Colorectal Neoplasms - etiology Construction Construction Materials - adverse effects Female Gastroenterology. Liver. Pancreas. Abdomen Humans Male Medical sciences Mesothelioma - epidemiology Mesothelioma - etiology Middle Aged Occupational Diseases - epidemiology Occupational Diseases - etiology Occupational Exposure - adverse effects Occupations Odds Ratio ORIGINAL ARTICLES Pleural Neoplasms - epidemiology Pleural Neoplasms - etiology Population Surveillance Risk Factors Smoking - adverse effects Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors |
title | Construction Occupations, Asbestos Exposure, and Cancer of the Colon and Rectum |
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