Construction Occupations, Asbestos Exposure, and Cancer of the Colon and Rectum

Colorectal cancer affects more than 157,000 Americans annually. Occupational risk from exposure to asbestos dust has been implicated, leading us to explore further the possible association between colorectal cancer and asbestos. Two hundred sixty-one cases of colon and rectal cancer and 183 control...

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Veröffentlicht in:Journal of occupational and environmental medicine 1994-09, Vol.36 (9), p.1027-1031
Hauptverfasser: Demers, Raymond Y., Burns, Patricia Brissette, Swanson, G. Marie
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container_title Journal of occupational and environmental medicine
container_volume 36
creator Demers, Raymond Y.
Burns, Patricia Brissette
Swanson, G. Marie
description Colorectal cancer affects more than 157,000 Americans annually. Occupational risk from exposure to asbestos dust has been implicated, leading us to explore further the possible association between colorectal cancer and asbestos. Two hundred sixty-one cases of colon and rectal cancer and 183 control cases were identified within a large, population-based case-control study conducted in southeast Michigan. Employment in occupations historically known to involve heavy exposure to asbestos was used as a surrogate for asbestos exposure. Cancers of the colon showed reduced odds ratios. Our findings differ substantially from those of the previous studies showing elevated risk. Further study is needed to address the same question, with specified asbestos exposure assessment and control for potentially significant confounders such as physical activity and diet.
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identifier ISSN: 0096-1736
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source MEDLINE; Journals@Ovid Complete
subjects Adult
Asbestos
Asbestos - adverse effects
Biological and medical sciences
Cocarcinogenesis
Colon cancer
Colorectal Neoplasms - epidemiology
Colorectal Neoplasms - etiology
Construction
Construction Materials - adverse effects
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Male
Medical sciences
Mesothelioma - epidemiology
Mesothelioma - etiology
Middle Aged
Occupational Diseases - epidemiology
Occupational Diseases - etiology
Occupational Exposure - adverse effects
Occupations
Odds Ratio
ORIGINAL ARTICLES
Pleural Neoplasms - epidemiology
Pleural Neoplasms - etiology
Population Surveillance
Risk Factors
Smoking - adverse effects
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
title Construction Occupations, Asbestos Exposure, and Cancer of the Colon and Rectum
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