Response of super-paramagnetic beads in microfluidic devices with integrated magnetic micro-columns
Ferromagnetic micro-columns (FMCs) have been fabricated on glass substrates using standard photolithography and electroplating and then integrated in micro-fluidic channels in order to study the response of super-paramagnetic beads suspended in an aqueous solution. We observed that under low externa...
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| Veröffentlicht in: | Microelectronic engineering 2006-04, Vol.83 (4), p.1655-1659 |
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| container_title | Microelectronic engineering |
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| creator | Guo, S.S. Zuo, C.C. Huang, W.H. Peroz, C. Chen, Y. |
| description | Ferromagnetic micro-columns (FMCs) have been fabricated on glass substrates using standard photolithography and electroplating and then integrated in micro-fluidic channels in order to study the response of super-paramagnetic beads suspended in an aqueous solution. We observed that under low external magnetic fields, the integrated micro-columns could generate sufficiently strong magnetic field gradients to trap super-paramagnetic beads in a flowing stream of water. The trapping behavior of the integrated FMCs was studied by considering different micro-patterns and different magnetic field intensities. In addition, the formation of magnetic micro-beads chains has been observed due to the magnetic dipole interactions. We believe that the integration of ferromagnetic micro-columns in micro-fluidic channels can have a variety of advanced applications, considering different possibilities of surface functionalization and manipulation of super-paramagnetic beads in an aqueous solution. |
| doi_str_mv | 10.1016/j.mee.2006.01.141 |
| format | Article |
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We believe that the integration of ferromagnetic micro-columns in micro-fluidic channels can have a variety of advanced applications, considering different possibilities of surface functionalization and manipulation of super-paramagnetic beads in an aqueous solution.</description><subject>Applied sciences</subject><subject>Electronics</subject><subject>Exact sciences and technology</subject><subject>Magnetic devices</subject><subject>micro-fluidics</subject><subject>micro-technology</subject><subject>Microelectronic fabrication (materials and surfaces technology)</subject><subject>Pattern</subject><subject>Semiconductor electronics. Microelectronics. Optoelectronics. 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Solid state devices</topic><topic>Super-paramagnetic beads</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guo, S.S.</creatorcontrib><creatorcontrib>Zuo, C.C.</creatorcontrib><creatorcontrib>Huang, W.H.</creatorcontrib><creatorcontrib>Peroz, C.</creatorcontrib><creatorcontrib>Chen, Y.</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Microelectronic engineering</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guo, S.S.</au><au>Zuo, C.C.</au><au>Huang, W.H.</au><au>Peroz, C.</au><au>Chen, Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Response of super-paramagnetic beads in microfluidic devices with integrated magnetic micro-columns</atitle><jtitle>Microelectronic engineering</jtitle><date>2006-04-01</date><risdate>2006</risdate><volume>83</volume><issue>4</issue><spage>1655</spage><epage>1659</epage><pages>1655-1659</pages><issn>0167-9317</issn><eissn>1873-5568</eissn><coden>MIENEF</coden><abstract>Ferromagnetic micro-columns (FMCs) have been fabricated on glass substrates using standard photolithography and electroplating and then integrated in micro-fluidic channels in order to study the response of super-paramagnetic beads suspended in an aqueous solution. 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| source | Elsevier ScienceDirect Journals Complete |
| subjects | Applied sciences Electronics Exact sciences and technology Magnetic devices micro-fluidics micro-technology Microelectronic fabrication (materials and surfaces technology) Pattern Semiconductor electronics. Microelectronics. Optoelectronics. Solid state devices Super-paramagnetic beads |
| title | Response of super-paramagnetic beads in microfluidic devices with integrated magnetic micro-columns |
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