Analysis of complications in transfemoral transcatheter aortic valve implantation: a single-center study

Transfemoral access is a prevailing approach for transcatheter aortic valve implantation (TAVI) in contemporary practice, with a shift from surgical arteriotomy to a percutaneous arterial approach. This study assessed long- and short‑term mortality, along with Valve Academic Research Consortium-2-de...

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Veröffentlicht in:Polskie archiwum medycyny wewne̦trznej 2024-04, Vol.134 (4)
Hauptverfasser: Pyłko, Anna, Dąbrowski, Maciej, Kowalik, Ilona, Chmielak, Zbigniew, Kukuła, Krzysztof, Wolny, Rafał, Kwieciński, Jacek, Stokłosa, Patrycjusz, Grabowski, Maciej, Michałowska, Ilona, Kuśmierski, Krzysztof, Witkowski, Adam
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container_title Polskie archiwum medycyny wewne̦trznej
container_volume 134
creator Pyłko, Anna
Dąbrowski, Maciej
Kowalik, Ilona
Chmielak, Zbigniew
Kukuła, Krzysztof
Wolny, Rafał
Kwieciński, Jacek
Stokłosa, Patrycjusz
Grabowski, Maciej
Michałowska, Ilona
Kuśmierski, Krzysztof
Witkowski, Adam
description Transfemoral access is a prevailing approach for transcatheter aortic valve implantation (TAVI) in contemporary practice, with a shift from surgical arteriotomy to a percutaneous arterial approach. This study assessed long- and short‑term mortality, along with Valve Academic Research Consortium-2-defined complications in percutaneous transfemoral approach (PTA) TAVI. Furthermore, it explored the impact of a learning curve on procedural outcomes. The study included 600 patients undergoing PTA TAVI at the National Institute of Cardiology, Warsaw, Poland, from January 2009 to September 2020. Retrospective data comparison involved 2 groups: early experience (first 200 patients) and late experience (next 400 patients). The primary end point (composite of life‑threatening bleeding, major vascular complication, or death at 30 days) occurred less often in the late experience group (28% vs 17.5%; P = 0.003). The late experience group also showed fewer cases of vascular complications (19% vs 10.7%; P = 0.005) and major bleeding (17.5% vs 8.5%; P = 0.001). Propensity matching yielded similar trends, including reduced frequency of pacemaker implantation (22.8% vs 10.9%; P = 0.03) and shorter median (interquartile range) hospitalization (11 [8-18] vs 7 [6-12] days; P
doi_str_mv 10.20452/pamw.16696
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This study assessed long- and short‑term mortality, along with Valve Academic Research Consortium-2-defined complications in percutaneous transfemoral approach (PTA) TAVI. Furthermore, it explored the impact of a learning curve on procedural outcomes. The study included 600 patients undergoing PTA TAVI at the National Institute of Cardiology, Warsaw, Poland, from January 2009 to September 2020. Retrospective data comparison involved 2 groups: early experience (first 200 patients) and late experience (next 400 patients). The primary end point (composite of life‑threatening bleeding, major vascular complication, or death at 30 days) occurred less often in the late experience group (28% vs 17.5%; P = 0.003). The late experience group also showed fewer cases of vascular complications (19% vs 10.7%; P = 0.005) and major bleeding (17.5% vs 8.5%; P = 0.001). Propensity matching yielded similar trends, including reduced frequency of pacemaker implantation (22.8% vs 10.9%; P = 0.03) and shorter median (interquartile range) hospitalization (11 [8-18] vs 7 [6-12] days; P &lt;0.001) in the late experience group. 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subjects Aged
Aged, 80 and over
Aortic Valve Stenosis - surgery
Female
Femoral Artery
Humans
Male
Poland
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Retrospective Studies
Transcatheter Aortic Valve Replacement - adverse effects
Transcatheter Aortic Valve Replacement - methods
Treatment Outcome
title Analysis of complications in transfemoral transcatheter aortic valve implantation: a single-center study
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