Intranodal palisaded myofibroblastome: A rare cause of inguinal lymphadenopathy

Lymphadenopathies are a major cause of consultation in internal medicine, with various causes of diagnosis. Unexplained persistent lymphadenopathy must be biopsied to rule out malignant tumor. We report the case of a 53-year-old man, with inguinal lymphadenopathy evolving for more than one year. The...

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Veröffentlicht in:La revue de medecine interne 2024-03, Vol.45 (3), p.138-141
Hauptverfasser: Gomes de Pinho, Q, Dales, J-P, Macagno, N, Houser, F, Delayre, T, Imbert-Joscht, I, Rossi, P, Benyamine, A, Granel, B
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container_end_page 141
container_issue 3
container_start_page 138
container_title La revue de medecine interne
container_volume 45
creator Gomes de Pinho, Q
Dales, J-P
Macagno, N
Houser, F
Delayre, T
Imbert-Joscht, I
Rossi, P
Benyamine, A
Granel, B
description Lymphadenopathies are a major cause of consultation in internal medicine, with various causes of diagnosis. Unexplained persistent lymphadenopathy must be biopsied to rule out malignant tumor. We report the case of a 53-year-old man, with inguinal lymphadenopathy evolving for more than one year. The patient had no associated symptoms and his blood tests were unremarkable. Due to the progression of the adenopathy and its hypermetabolism on PET-CT, an excisional biopsy was performed. Histological analysis revealed an intranodal proliferation of spindle cells with a palisading pattern. β-catenine and smooth muscle actin labelling were positive, leading to the diagnosis of intranodal palisaded myofibroblastoma, a benign tumour. Intranodal palisaded myofibroblastoma is a rare benign cause of adenopathy, with often inguinal lymph node localization and slow growth and without risk of recurrence after surgical removal.
doi_str_mv 10.1016/j.revmed.2023.10.439
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title Intranodal palisaded myofibroblastome: A rare cause of inguinal lymphadenopathy
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