Characterization of a Nonselective Opioid Receptor Functional Antagonist: Implications for Development as a Novel Opioid Dependence Medication

Opioids represent the most extensive category of abused substances in the United States, and the number of fatalities caused by these drugs exceeds those associated with all other drug overdoses combined. The administration of naltrexone, a potent pan-opioid receptor antagonist, to an individual dep...

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Veröffentlicht in:ACS pharmacology & translational science 2024-03, Vol.7 (3), p.654-666
Hauptverfasser: Shahbazi Nia, Siavash, Ortiz, Yuma T., Zuarth Gonzalez, Julio D., Shamir, Leila, Frimpong-Manson, Kofi, Hossain, Mohammad Anwar, Shahi, Sadisna, Bandy, Rayna, Bhat, Anoushka, Patel, Dhavalkumar, Diab, Hanin, Thompson, Jonathan, McMahon, Lance R., Wilkerson, Jenny L., German, Nadezhda A.
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Sprache:eng
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