Exploiting the therapeutic implications of KRAS inhibition on tumor immunity

Over the past decade, RAS oncogenic proteins have transitioned from being deemed undruggable to having two clinically approved drugs, with several more in advanced stages of development. Despite the initial benefit of KRAS-G12C inhibitors for patients with tumors harboring this mutation, the rapid e...

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Veröffentlicht in:Cancer cell 2024-03, Vol.42 (3), p.338-357
Hauptverfasser: Molina-Arcas, Miriam, Downward, Julian
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
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