Reducing brain Aβ burden ameliorates high-fat diet-induced fatty liver disease in APP/PS1 mice

High-fat diet (HFD)-induced fatty liver disease is a deteriorating risk factor for Alzheimer’s disease (AD). Mitigating fatty liver disease has been shown to attenuate AD-like pathology in animal models. However, it remains unclear whether enhancing Aβ clearance through immunotherapy would in turn a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomedicine & pharmacotherapy 2024-04, Vol.173, p.116404-116404, Article 116404
Hauptverfasser:	Tsay, Huey-Jen, Gan, Yu-Ling, Su, Yu-Han, Sun, Yu-Yo, Yao, Heng-Hsiang, Chen, Hui-Wen, Hsu, Ying-Ting, Hsu, John Tsu-An, Wang, Horng-Dar, Shie, Feng-Shiun
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Alzheimer’s disease Amyloid beta-Peptides - metabolism Amyloid beta-Protein Precursor - metabolism Animals Anti-Aβ antibody Brain - metabolism Diet, High-Fat - adverse effects Disease Models, Animal Fatty liver Fatty Liver - metabolism High-fat diet Liver Diseases - metabolism Mice Mice, Transgenic Microglial phagocytosis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!