Dendronized Polymer‐Derived Nanomedicines for Mitochondrial Dynamics Regulation and Immune Modulation

The effects of dendron side chains in polymeric conjugates on tumor penetration and antigen presentation are systematically examined. Three polymer‐gemcitabine (Gem) conjugates (pG0‐Gem, pG1‐Gem, pG2‐Gem) are designed and prepared. The pG2‐Gem conjugate uniquely binds to the mitochondria of tumor ce...

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Veröffentlicht in:	Advanced materials (Weinheim) 2024-06, Vol.36 (25), p.e2400582-n/a
Hauptverfasser:	Hou, Xingyu, Pan, Dayi, Zhong, Dan, Gong, Qiyong, Luo, Kui
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen presentation Antigens Conjugates dendronized polymers drug penetration Mitochondria mitochondrial dynamics Modulation Polymers tumor immunotherapy
Online-Zugang:	Volltext
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