Cavernous Malformations of the Central Nervous System
Cerebral cavernous malformations occur in 0.5% of the population; 85% are sporadic, and 15% are familial or radiation-induced. Several genetic variants, including variants in CCM , drive their development.
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| Veröffentlicht in: | The New England journal of medicine 2024-03, Vol.390 (11), p.1022-1028 |
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| container_title | The New England journal of medicine |
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| creator | Smith, Edward R. |
| description | Cerebral cavernous malformations occur in 0.5% of the population; 85% are sporadic, and 15% are familial or radiation-induced. Several genetic variants, including variants in
CCM
, drive their development. |
| doi_str_mv | 10.1056/NEJMra2305116 |
| format | Article |
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CCM
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| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2024-03, Vol.390 (11), p.1022-1028 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
| subjects | CCM2 protein Cell division Central Nervous System Gadolinium Genetics Genetics General Hemorrhage Humans Hypotheses Kinases Magnetic resonance imaging Nervous system Neurology Neurosurgery Neurosurgery General Pathogenesis Pediatrics Pediatrics General Polymerization Radiation Radiation therapy Radiology Radiology General Seizures Surgery Surgery General |
| title | Cavernous Malformations of the Central Nervous System |
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