2,4,5-Triaminopyrimidines as blue fluorescent probes for cell viability monitoring: synthesis, photophysical properties, and microscopy applications

Monitoring cell viability is critical in cell biology, pathology, and drug discovery. Most cell viability assays are cell-destructive, time-consuming, expensive, and/or hazardous. Herein, we present a series of newly synthesized 2,4,5-triaminopyrimidine derivatives able to discriminate between live...

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Veröffentlicht in:	Organic & biomolecular chemistry 2024-03, Vol.22 (11), p.2252-2263
Hauptverfasser:	Gonçalves, Jorge M, Gonçalves, João N. D, Sousa, Luís F, Rodrigues, Lígia R, Correia-de-Sá, Paulo, Coutinho, Paulo J. G, Castanheira, Elisabete M. S, Oliveira, Rui, Dias, Alice M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Survival Cell viability Chemical synthesis Emission Emissions Fluorescent Dyes Fluorescent indicators Grooves Microscopy Monitoring Visible spectrum Wavelengths
Online-Zugang:	Volltext
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