Characterization of degradation kinetics of additively manufactured PLGA under variable mechanical loading paradigms

Controlled degradation of biodegradable poly-lactic-co-glycolic acid (PLGA) trauma implants may increase interfragmentary loading which is known to accelerate fracture healing. Additive manufacturing allows us to tune the mechanical properties of PLGA scaffolds; however, little is known about this n...

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Veröffentlicht in:	Journal of the mechanical behavior of biomedical materials 2024-05, Vol.153, p.106457-106457, Article 106457
Hauptverfasser:	Smith, Anna N., Ulsh, Joseph B., Gupta, Richa, Tang, My My, Peredo, Ana P., Teinturier, Tim D., Mauck, Rob L., Gullbrand, Sarah, Hast, Michael W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbable Implants Additive manufacturing Animals Biomaterials Biomechanics Degradation Glycols Mechanical Phenomena PLGA Polyglycolic Acid Polylactic Acid-Polyglycolic Acid Copolymer Porosity Rats Trauma implants
Online-Zugang:	Volltext
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