Leaf Extract from European Olive (Olea europaea L.) Post-Transcriptionally Suppresses the Epithelial-Mesenchymal Transition and Sensitizes Gastric Cancer Cells to Chemotherapy

The overall survival of patients with the advanced and recurrent gastric cancer (GC) remains unfavorable. In particular, this is due to cancer spreading and resistance to chemotherapy associated with the epithelial-mesenchymal transition (EMT) of tumor cells. EMT can be identified by the transcripto...

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Veröffentlicht in:	Biochemistry (Moscow) 2024, Vol.89 (1), p.97-115
Hauptverfasser:	Tekin, Cagla, Ercelik, Melis, Dunaev, Pavel, Galembikova, Aigul, Tezcan, Gulcin, Aksoy, Secil Ak, Budak, Ferah, Isık, Ozgen, Ugras, Nesrin, Boichuk, Sergei, Tunca, Berrin
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil Annexin V Anticancer properties Antineoplastic drugs Antitumor activity Apoptosis Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Cadherins Cadherins - metabolism Cancer therapies Cell Line, Tumor Cell Movement Chemotherapy Cisplatin Cisplatin - pharmacology Epithelial-Mesenchymal Transition Fluorouracil - pharmacology Gastric cancer Gene expression Gene Expression Regulation, Neoplastic Herbal medicine Humans Invasiveness Leaves Life Sciences Microbiology Olea - metabolism Plant extracts Plant Extracts - pharmacology Post-transcription Snail protein Stomach Neoplasms - drug therapy Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Survival Survival analysis Transcription factors Transcriptomes Tumor cells Tumors Vimentin
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