Heart rate score in remote monitoring: An additional tool for predicting outcomes in heart failure with reduced ejection fraction

Heart rate score (HRS) ≥ 70% has been associated with arrhythmic events and mortality but these studies were not specific for heart failure (HF) patients. We hypothesized that HRS ≥ 70% obtained from remote monitoring (RM) is associated with HF hospitalizations and arrhythmic events in HF with reduc...

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Veröffentlicht in:Pacing and clinical electrophysiology 2024-04, Vol.47 (4), p.490-495
Hauptverfasser: Barradas, Maria Inês, Coutinho Dos Santos, Inês, Duarte, Fabiana, Viveiros Monteiro, André, Tavares, Anabela, Martins, Dinis
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container_end_page 495
container_issue 4
container_start_page 490
container_title Pacing and clinical electrophysiology
container_volume 47
creator Barradas, Maria Inês
Coutinho Dos Santos, Inês
Duarte, Fabiana
Viveiros Monteiro, André
Tavares, Anabela
Martins, Dinis
description Heart rate score (HRS) ≥ 70% has been associated with arrhythmic events and mortality but these studies were not specific for heart failure (HF) patients. We hypothesized that HRS ≥ 70% obtained from remote monitoring (RM) is associated with HF hospitalizations and arrhythmic events in HF with reduced ejection fraction (HFrEF). HRS was calculated from RM in patients with HFrEF and ICD or CRT-D. Two groups were defined: HRS ≥ 70% (G1, n = 55) and HRS 
doi_str_mv 10.1111/pace.14961
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We hypothesized that HRS ≥ 70% obtained from remote monitoring (RM) is associated with HF hospitalizations and arrhythmic events in HF with reduced ejection fraction (HFrEF). HRS was calculated from RM in patients with HFrEF and ICD or CRT-D. Two groups were defined: HRS ≥ 70% (G1, n = 55) and HRS &lt; 70% (G2, n = 48) RESULTS: A total of 103 patients were included (64.4 ± 13.04 years, 69.9% male, mean left ventricular ejection fraction (LVEF) 33.62 ± 11.97% and FUP 61.7 ± 38.87 months). The device was CRT-D in 59.2% and ICD in 40.8% and the majority (90.3%) had the device implanted in primary prevention. G1 patients were more frequently male (p = .017) and had more coronary disease (p = .035). HRS ≥70% was an independent predictor for unplanned HF hospitalizations (OR: 1.905 (95% CI: 1.328-3.649), p &lt; .001)). The indication for device implantation (primary vs. secondary prevention), type of device, NYHA class, age, gender and LVEF were not independent predictors of the outcome. VF (4.9 ± 20.0 G1 vs. 1.1 ± 5.47 G2, p = .046) and VT episodes were more prevalent in G1 (3.1 ± 8.93 G1 vs. 0.3 ± 1.59 G2, p = .026), as well as appropriate device shocks (4.3 ± 12.06 G1 vs. 0.3 ± 1.49 G2, p = .023). There was no difference in inappropriate shocks or mortality outcomes between groups. HRS ≥70% obtained from RM was an independent predictor of HF hospitalizations and was associated with arrhythmic events with VT and VF episodes and appropriate device shocks in HFrEF patients.</description><identifier>ISSN: 0147-8389</identifier><identifier>EISSN: 1540-8159</identifier><identifier>DOI: 10.1111/pace.14961</identifier><identifier>PMID: 38462714</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Congestive heart failure ; Ejection fraction ; Heart diseases ; Heart failure ; Heart rate ; Hospitalization ; Mortality</subject><ispartof>Pacing and clinical electrophysiology, 2024-04, Vol.47 (4), p.490-495</ispartof><rights>2024 Wiley Periodicals LLC.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c274t-e279b5c26a148096f738c407d3bdf2199d093f59b46e13d77dda0114b12a84ac3</cites><orcidid>0000-0003-0165-6645</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38462714$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Barradas, Maria Inês</creatorcontrib><creatorcontrib>Coutinho Dos Santos, Inês</creatorcontrib><creatorcontrib>Duarte, Fabiana</creatorcontrib><creatorcontrib>Viveiros Monteiro, André</creatorcontrib><creatorcontrib>Tavares, Anabela</creatorcontrib><creatorcontrib>Martins, Dinis</creatorcontrib><title>Heart rate score in remote monitoring: An additional tool for predicting outcomes in heart failure with reduced ejection fraction</title><title>Pacing and clinical electrophysiology</title><addtitle>Pacing Clin Electrophysiol</addtitle><description>Heart rate score (HRS) ≥ 70% has been associated with arrhythmic events and mortality but these studies were not specific for heart failure (HF) patients. We hypothesized that HRS ≥ 70% obtained from remote monitoring (RM) is associated with HF hospitalizations and arrhythmic events in HF with reduced ejection fraction (HFrEF). HRS was calculated from RM in patients with HFrEF and ICD or CRT-D. Two groups were defined: HRS ≥ 70% (G1, n = 55) and HRS &lt; 70% (G2, n = 48) RESULTS: A total of 103 patients were included (64.4 ± 13.04 years, 69.9% male, mean left ventricular ejection fraction (LVEF) 33.62 ± 11.97% and FUP 61.7 ± 38.87 months). The device was CRT-D in 59.2% and ICD in 40.8% and the majority (90.3%) had the device implanted in primary prevention. G1 patients were more frequently male (p = .017) and had more coronary disease (p = .035). HRS ≥70% was an independent predictor for unplanned HF hospitalizations (OR: 1.905 (95% CI: 1.328-3.649), p &lt; .001)). The indication for device implantation (primary vs. secondary prevention), type of device, NYHA class, age, gender and LVEF were not independent predictors of the outcome. VF (4.9 ± 20.0 G1 vs. 1.1 ± 5.47 G2, p = .046) and VT episodes were more prevalent in G1 (3.1 ± 8.93 G1 vs. 0.3 ± 1.59 G2, p = .026), as well as appropriate device shocks (4.3 ± 12.06 G1 vs. 0.3 ± 1.49 G2, p = .023). There was no difference in inappropriate shocks or mortality outcomes between groups. HRS ≥70% obtained from RM was an independent predictor of HF hospitalizations and was associated with arrhythmic events with VT and VF episodes and appropriate device shocks in HFrEF patients.</description><subject>Congestive heart failure</subject><subject>Ejection fraction</subject><subject>Heart diseases</subject><subject>Heart failure</subject><subject>Heart rate</subject><subject>Hospitalization</subject><subject>Mortality</subject><issn>0147-8389</issn><issn>1540-8159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNpdkctKxDAUQIMoOo5u_AAJuBGhmlfbxJ2ILxDc6Lqkya1maJsxSRGX_rmZGXVhNjcXDgcuB6EjSs5pfhdLbeCcClXRLTSjpSCFpKXaRjNCRV1ILtUe2o9xQQipiCh30R6XomI1FTP0dQ86JBx0AhyND4DdiAMMPu-DH13ywY2vl_hqxNpal5wfdY-T9z3ufMDLANaZlBHsp2T8AHEleFtLO-36KRs_XHrLTjsZsBgWYFYW3AW9_hygnU73EQ5_5hy93N48X98Xj093D9dXj4VhtUgFsFq1pWGVpkISVXU1l0aQ2vLWdowqZYniXalaUQHltq6t1YRS0VKmpdCGz9HpxrsM_n2CmJrBRQN9r0fwU2yYKktWyZLwjJ78Qxd-Cvnw2HDCmVJESZGpsw1lgo8xQNcsgxt0-GwoaVZhmlWYZh0mw8c_yqkdwP6hvyX4N9KAihE</recordid><startdate>20240401</startdate><enddate>20240401</enddate><creator>Barradas, Maria Inês</creator><creator>Coutinho Dos Santos, Inês</creator><creator>Duarte, Fabiana</creator><creator>Viveiros Monteiro, André</creator><creator>Tavares, Anabela</creator><creator>Martins, Dinis</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0165-6645</orcidid></search><sort><creationdate>20240401</creationdate><title>Heart rate score in remote monitoring: An additional tool for predicting outcomes in heart failure with reduced ejection fraction</title><author>Barradas, Maria Inês ; Coutinho Dos Santos, Inês ; Duarte, Fabiana ; Viveiros Monteiro, André ; Tavares, Anabela ; Martins, Dinis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c274t-e279b5c26a148096f738c407d3bdf2199d093f59b46e13d77dda0114b12a84ac3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Congestive heart failure</topic><topic>Ejection fraction</topic><topic>Heart diseases</topic><topic>Heart failure</topic><topic>Heart rate</topic><topic>Hospitalization</topic><topic>Mortality</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Barradas, Maria Inês</creatorcontrib><creatorcontrib>Coutinho Dos Santos, Inês</creatorcontrib><creatorcontrib>Duarte, Fabiana</creatorcontrib><creatorcontrib>Viveiros Monteiro, André</creatorcontrib><creatorcontrib>Tavares, Anabela</creatorcontrib><creatorcontrib>Martins, Dinis</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Pacing and clinical electrophysiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barradas, Maria Inês</au><au>Coutinho Dos Santos, Inês</au><au>Duarte, Fabiana</au><au>Viveiros Monteiro, André</au><au>Tavares, Anabela</au><au>Martins, Dinis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heart rate score in remote monitoring: An additional tool for predicting outcomes in heart failure with reduced ejection fraction</atitle><jtitle>Pacing and clinical electrophysiology</jtitle><addtitle>Pacing Clin Electrophysiol</addtitle><date>2024-04-01</date><risdate>2024</risdate><volume>47</volume><issue>4</issue><spage>490</spage><epage>495</epage><pages>490-495</pages><issn>0147-8389</issn><eissn>1540-8159</eissn><abstract>Heart rate score (HRS) ≥ 70% has been associated with arrhythmic events and mortality but these studies were not specific for heart failure (HF) patients. We hypothesized that HRS ≥ 70% obtained from remote monitoring (RM) is associated with HF hospitalizations and arrhythmic events in HF with reduced ejection fraction (HFrEF). HRS was calculated from RM in patients with HFrEF and ICD or CRT-D. Two groups were defined: HRS ≥ 70% (G1, n = 55) and HRS &lt; 70% (G2, n = 48) RESULTS: A total of 103 patients were included (64.4 ± 13.04 years, 69.9% male, mean left ventricular ejection fraction (LVEF) 33.62 ± 11.97% and FUP 61.7 ± 38.87 months). The device was CRT-D in 59.2% and ICD in 40.8% and the majority (90.3%) had the device implanted in primary prevention. G1 patients were more frequently male (p = .017) and had more coronary disease (p = .035). HRS ≥70% was an independent predictor for unplanned HF hospitalizations (OR: 1.905 (95% CI: 1.328-3.649), p &lt; .001)). The indication for device implantation (primary vs. secondary prevention), type of device, NYHA class, age, gender and LVEF were not independent predictors of the outcome. VF (4.9 ± 20.0 G1 vs. 1.1 ± 5.47 G2, p = .046) and VT episodes were more prevalent in G1 (3.1 ± 8.93 G1 vs. 0.3 ± 1.59 G2, p = .026), as well as appropriate device shocks (4.3 ± 12.06 G1 vs. 0.3 ± 1.49 G2, p = .023). There was no difference in inappropriate shocks or mortality outcomes between groups. HRS ≥70% obtained from RM was an independent predictor of HF hospitalizations and was associated with arrhythmic events with VT and VF episodes and appropriate device shocks in HFrEF patients.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>38462714</pmid><doi>10.1111/pace.14961</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-0165-6645</orcidid></addata></record>
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subjects Congestive heart failure
Ejection fraction
Heart diseases
Heart failure
Heart rate
Hospitalization
Mortality
title Heart rate score in remote monitoring: An additional tool for predicting outcomes in heart failure with reduced ejection fraction
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