Manganese accumulation in red blood cells as a biomarker of manganese exposure and neurotoxicity

Although overexposure to manganese (Mn) is known to cause neurotoxic damage, effective exposure markers for assessing Mn loading in Mn-exposed workers are lacking. Here, we construct a Mn-exposed rat model to perform correlation analysis between Mn-induced neurological damage and Mn levels in variou...

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Veröffentlicht in:	Neurotoxicology (Park Forest South) 2024-05, Vol.102, p.1-11
Hauptverfasser:	Deng, Xuedan, Guo, Yonghua, Jin, Xiaofei, Si, Huifang, Dai, Kai, Deng, Meng, He, Jing, Hao, Changfu, Yao, Wu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - blood Biomarkers - urine Erythrocytes - drug effects Erythrocytes - metabolism Exposure biomarker Female Humans Male Manganese Manganese - blood Manganese - toxicity Manganese - urine Manganese Poisoning - blood Neurotoxicity Neurotoxicity Syndromes - blood Neurotoxicity Syndromes - etiology Occupational Exposure - adverse effects Rats Rats, Sprague-Dawley Red blood cells
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