Allergic rhinitis: therapeutic strategies update Lactococcus lactis Plasma and tranilast-roxithromycin combination

* At present, there is no established definitive and reliable therapy for allergic rhinitis. * Combined effects of tranilast, which inhibits mast cell degranulation, and a specific macrolide antibiotic, roxithromycin, which has T helper 2 (Th2) cell inhibitory effects through ligands and receptors,...

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Veröffentlicht in:Allergologia et immunopathologia 2024-01, Vol.52 (2), p.1-2
1. Verfasser: Horiuchi, Yasuhiro
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description * At present, there is no established definitive and reliable therapy for allergic rhinitis. * Combined effects of tranilast, which inhibits mast cell degranulation, and a specific macrolide antibiotic, roxithromycin, which has T helper 2 (Th2) cell inhibitory effects through ligands and receptors, may aid significantly in managing allergic rhinitis. * Lactococcus lactis strain Plasma (LC-Plasma) can induce plasmacytoid dendritic cells and consistent intake of LC-Plasma increases T helper 1 (Th1) responses, indicating a potential to suppress Th2 hypersensitivity conditions, such as allergic rhinitis. * A novel treatment approach for hay fever can now be chosen based on to the severity of the disease and amount of scattered pollen.
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subjects Allergies
Antigens
Conflicts of interest
Dendritic cells
Dermatitis
Drugs
Erythema
Hay fever
Humans
Lactococcus lactis
ortho-Aminobenzoates - therapeutic use
Patients
Plasma
Probiotics
Rhinitis
Rhinitis, Allergic - drug therapy
Roxithromycin - therapeutic use
title Allergic rhinitis: therapeutic strategies update Lactococcus lactis Plasma and tranilast-roxithromycin combination
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