Potential targets of diosgenin for the treatment of oral squamous cell carcinoma and their bioinformatics and transcriptional profiling analyses

•There were 146 potential targets of diosgenin for OSCC treatment.•The genes such as AKT1, MET1, SRC1, and PTGS2 may be important targets.•Diosgenin significantly inhibited HSC-3 cell activity.•Th expression of the targets was regulated by diosgenin.•Their proteins of targets had a high binding ener...

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Veröffentlicht in:	Steroids 2024-05, Vol.205, p.109393-109393, Article 109393
Hauptverfasser:	Xiao, Yang, Xu, Bingbing, Li, Xiaolan, Ding, Tianhao, Zhao, Wenxin, Nie, Xiaoxue, Mu, Junxia, Xiao, Zhiyou, Wang, Qian, Ren, Qunli, Zhang, Enkui
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Diosgenin OSCC Signaling pathway Targets Transcriptional profiling
Online-Zugang:	Volltext
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